The carefully crafted formulas to help you be younger for longer
NOVOS Core is made of 12 natural, FDA-approved ingredients that synergistically target 12 causes of aging. This approach is backed by our team of longevity experts from Harvard, MIT, and more. See each ingredient below, including the role each plays in longevity and the science behind them.
Fisetin has shown to extend lifespan in animals. Fisetin helps the body to manage senescent cells, and can combat inflammaging at the cellular level.
Glycine has shown to extend lifespan in different species. In humans, higher glycine levels are associated with heart health, combating inflammaging at the cellular level, and supporting glucose metabolism.
Pterostilbene, a natural substance found in blueberries, is better absorbable and lasts longer in the body than resveratrol, a compound that has shown to extend lifespan in different species. Pterostilbene can target inflammaging at a cellular level and contribute to a healthy epigenome and DNA stability.
Rhodiola extends lifespan in different species. Substances in Rhodiola, like salidroside, have shown to support nerve regeneration in animals, normal sirtuin and AMPK function in human cells, and help the body to manage senescent cells.
Various studies found that people who take micro doses of lithium live longer. In human studies, supplementing with micro-dosed lithium supports healthy brain aging. Micro doses of lithium extend lifespan in multiple species.
Alpha-ketoglutarate (AKG) extends lifespan and healthspan in different species. In humans, alpha-ketoglutarate has shown to protect cells against damage and stressors. Alpha-ketoglutarate supports a healthy metabolism and a healthy epigenome.
Malate (as Magnesium Malate)
Malate is a natural substance found in apples which has shown to extend lifespan in organisms. Malate can support healthy energy levels in humans. Note: Malate and Magnesium come together as Mg Malate.
Glucosamine can help to lower aging-related low-grade inflammation (inflammaging) and can extend lifespan in various organisms. It can also mimic a calorie-restricted diet and induce the formation of new mitochondria.
Magnesium (as Magnesium Malate)
People who supplement with magnesium have shown to have less DNA damage. Magnesium supports a healthy metabolism and targets inflammation at the cellular level. Note: Malate and Magnesium come together as Mg Malate.
Hyaluronic acid can reduce the appearance of wrinkles when taken orally. A component of hyaluronic acid, acetyl-glucosamine, has shown to extend lifespan in animals.
Theanine is one of the substances responsible for the healthy effects of green tea. Theanine can extend lifespan in different organisms. It can increase the production of aging-protective proteins, like FOXO1 and antioxidative enzymes and can help the body to manage crosslinks.
Vitamin C can help to maintain a proper epigenome, especially in combination with another longevity ingredient, alpha-ketoglutarate.
Ginger can protect cells against damage and has various longevity-promoting effects. In humans, ginger can target inflammaging at a cellular level, can help to maintain proper glucose levels and support a healthy metabolism, and help to mitigate oxidative damage in cells
In humans, nicotinamide mononucleotide (NMN) increases levels of NAD+, which is needed for proper DNA repair and to maintain the epigenome. NMN has shown to support a healthy metabolism in humans, and improve muscle strength and performance in the elderly. In animals, NMN slows down various aging processes.
Please find 190+ scientific references here.