We target the 10 primary causes of aging using a patent-pending, science-backed formula
Most anti-aging companies lack understanding of what causes aging. At best, they may address signs of aging, without impacting underlying causes.
NOVOS is the only company to target the 10 causes of aging using multiple proven ingredients – an approach backed by top scientists and 190+ studies.
What ages your body? The latest scientific research uncovered 10 key causes:
01 Mitochondrial Dysfunction
During aging, mitochondria — the power plants of our cells — become dysfunctional. Without adequate power, cells — and by extension, organs — are not able to perform as well as when they were young.
Substances that promote healthy mitochondrial function: Malate | Glycine | Alpha-ketoglutarate | Fisetin | Glucosamine | Vitamin C | Pterostilbene
02 Cellular Senescence
Senescent cells are former healthy cells that stopped dividing and secrete substances that damage healthy surrounding cells. Commonly referred to as “zombie cells,” these cells increase exponentially with age and lead to tissue and organ damage.
Substances that help the body the manage senescent cells: Fisetin
03 Loss of Proteostasis
Over time, more and more proteins accumulate inside and outside our cells. These proteins should be cleaned up, and when they aren’t, interfere with the cells’ proper functioning.
Substances that help cells to properly recycle proteins: Lithium | Glycine | Glucosamine | Fisetin
04 Altered Cellular Communication
When we get older, our cells become increasingly exposed to a hostile environment, characterized by pro-inflammatory and other deleterious substances that hinder cells, including stem cells, to function properly.
Substances that support a healthy inflammatory response: Ginger | Fisetin | Glucosamine
05 Genomic Instability
During aging, our DNA becomes damaged, especially in stem cells and fast-dividing cells. Damaged DNA may result in improper cell function which impacts proper functioning of tissues and organs.
Substances that help to protect DNA: Pterostilbene | Glucosamine | Magnesium
06 Epigenetic Alterations
During aging, the epigenome — the molecular machinery that regulates our genes’ activity — becomes disorganized. This leads to certain beneficial genes being turned off when they should be on, and genes that can cause trouble being turned on when they should be off.
Substances that support a healthy epigenome: Lithium | Glycine | Alpha-ketoglutarate | Vitamin C | Ginger | Pterostilbene
07 Telomere Shortening
As we age, the ends of chromosomes, known as telomeres, get shorter and cannot protect DNA any longer. This can increase the likelihood of genomic instability and impair cell function.
Substances that support telomere health: Lithium | Magnesium | Pterostilbene
08 Deregulated Nutrient Sensing
During aging, our cells become less tuned to nutrient signals, which disrupts a cell’s ability to utilize and produce energy. This can result in reduced energy and metabolic dysfunction.
Substances that support a proper nutrient metabolism: Fisetin | Pterostilbene | Ginger | Magnesium Malate | NMN | Glycine
09 Stem Cell Exhaustion
With age, stem cells become dysfunctional or die off. Since stem cells are responsible for producing new copies of our cells when they’re needed, having fewer or dysfunctional stem cells leads to our tissues being less replenished & maintained.
Substances that support stem cell health: Glycine | Alpha-ketoglutarate
As we grow older, sugar-derived bonds, or crosslinks, are formed between the proteins that make up our tissues, making tissues more stiff. Stiffer tissue is less capable of performing its function than soft, supple tissue, especially in blood vessels, the lungs and the skin.
Substances that help the body to manage crosslinks: Glycine | L-Theanine | Glucosamine
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