Study finds NOVOS Core extends aged mouse lifespan beyond previously studied supplements. Learn More.
Studies Show NOVOS Protects Against DNA Damage & Senescence. Learn More.

Feel Younger
for Longer

Developed with Harvard & MIT scientists. Studied in randomized, placebo-controlled human research.

Available at Mayo Clinic Store & select health retailers • Recommended by 1,500+ clinicians • 7+ years R&D

Supports cellular energy production

Supports cognitive resilience

Helps maintain skin structure & elasticity

Supports healthy blood flow and vessel structure

Targets 12 biological Hallmarks of Aging

Supports cellular energy production

Supports cognitive resilience

Helps maintain skin structure & elasticity

Supports healthy blood flow and vessel structure

Targets 12 biological Hallmarks of Aging

Built On Human Evidence, Not Marketing

Targets The 12 Hallmarks Of Aging

Developed using the modern scientific framework of aging biology, years ahead of the field.

Clinically Studied As A Complete Formulation

Backed by 7+ years of R&D, NOVOS Core Clinical was studied as a complete formula, including randomized, placebo-controlled human research, not inferred from isolated ingredient studies.

Trusted By MDs & Leading Medical Institutions

Available at Mayo Clinic Store and Bumrungrad International Hospital (Newsweek Top 100 Global Hospital), and recommended by 1,500+ MDs & clinicians.

“NOVOS takes a disciplined, biology-first approach in a space that too often prioritizes hype over evidence.”

— Dr. Doina Kulick, Lead Physician, Longevity Medicine, Mayo Clinic Arizona


Science You Can Trust

Placebo-controlled
Human Research

Formulated by Harvard
& MIT Scientists

Patent-pending
Formulation

Preclinical
Lifespan Research

// YOUNGER FOR LONGER // YOUNGER FOR LONGER

// YOUNGER FOR LONGER // YOUNGER FOR LONGER

// YOUNGER FOR LONGER // YOUNGER FOR LONGER

// YOUNGER FOR LONGER // YOUNGER FOR LONGER

// YOUNGER FOR LONGER // YOUNGER FOR LONGER

Human Clinical Trial Results

In a randomized, double-blind, placebo-controlled human clinical trial, NOVOS Core Clinical demonstrated statistically significant improvements versus placebo across validated cardiovascular biomarkers used in aging research.*

Endothelial Function (Circulation)


NOVOS Core Clinical supported healthy endothelial responsiveness with sustained effects measuring approximately 1.26x to 4.65x of leading studied supplements, outperforming tea polyphenols, cocoa flavanols, beetroot nitrates, and demonstrating effects comparable to those reported for weight loss, aerobic exercise, and resistance training.*

Arterial Flexibility (Blood Vessels)


NOVOS Core Clinical helped support healthy arterial flexibility with effect sizes exceeding those reported for magnesium and omega-3s, and comparable to published results for weight loss, DASH heart health diets, and structured exercise — an effect rarely observed with dietary supplements.*

Systolic Blood Pressure Support


Supported ~8.5–8.7 mmHg differences in systolic blood pressure vs. placebo in adults already in the normal range, exceeding effect sizes reported for common supplements including beetroot/nitrate and potassium, and demonstrating magnitudes of support comparable to those observed for Mediterranean and DASH-style diets and High Intensity Interval Training (HIIT).*

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Validated Across Three Levels of Research

Clinically studied with multiple aging-relevant outcomes far exceeding placebo.

Human Clinical Trial

Tested in living mice and found to extend lifespan more than 18%**

Preclinical Lifespan Study

Tested on human cells to uncover its positive effects on causes of aging.**

Cellular Mechanism Studies

Clinically studied with multiple aging-relevant outcomes far exceeding placebo.

Human Clinical Trial

Tested in living mice and found to extend lifespan more than 18%**

Preclinical Lifespan Study

Tested on human cells to uncover its positive effects on causes of aging.**

Cellular Mechanism Studies

**Results from in vitro and animal studies are preclinical and do not necessarily translate to outcomes in humans. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

81% of customers

notice meaningful improvements in skin, mood, energy, or sleep within two weeks of taking NOVOS Core Clinical*.

Other benefits like vascular function may not be perceptible but reached statistically significant improvements in placebo-controlled human research*.

*Results based on post-purchase customer surveys and clinical results reflect outcomes observed in a randomized, placebo-controlled study population. Individual experiences may vary.

Trusted By a Global Community

Rated 4.8 out of 5 stars

Based on more than 1330 reviews

10+ Million Servings Taken

Loyal customers have taken NOVOS for 5+ years

Slower Pace of Aging**

Based on epigenetic biological age test results

Real People. Measurable Change.

Inventing the Future of Longevity

NOVOS Core Clinical is Built on Human Evidence

How NOVOS works

A Smarter Way To Age Well

Measure
Biological Age Testing

Understand your biological age with free tools like NOVOS LifeFaceAge. Dive deeper with NOVOS Age.

Optimize
Apply Science That Works

Apply science-backed protocols and tools for long-term health.

Core
NOVOS Core Clinical

Start with NOVOS Core Clinical, then add targeted products as needed.

Track Results
Track Your Progress

Monitor progress over time.

Built Alongside World-Class Scientists in Aging Biology

Scientific advisors and collaborators from Harvard, MIT, the Salk Institute, and leading medical institutions help guide our research, formulation, and innovation.

Dr George Church

Dr. George Church, PhD

“I see NOVOS as inspiring — they approach aging as a complex phenomenon, aiming at all pathways and hallmarks of aging simultaneously.”
Harvard Medical School & MIT Professor
Dr Pamela Maher

Dr. Pamela Maher, PhD

“What really impressed me about NOVOS was the comprehensiveness of their analysis of aging research to design their product.”
Salk Institute & University of British Columbia
dr j pedro magalhaes novos

Dr. J. Pedro Magalhães, PhD

“NOVOS has been using a novel science-based approach for developing its formulation. [They are] a leader in the longevity space.”
Harvard Medical School
dr robert lufkin novos

Dr. Robert Lufkin, MD

“It’s the rigorously-researched, science-backed formulations that set NOVOS apart in the longevity supplements space.”
USC School of Medicine Professor

Scientific advisors provide research guidance. Individual views expressed are their own.

Perspectives From Leading Longevity Scientists

Independent experts share their perspective on NOVOS’ research-driven approach to longevity.

Dr. George Church, PhD
Professor of Genetics, Harvard Medical School & MIT
NOVOS Scientific Advisory Board
Dr. Matt Kaeberlein, PhD
Frmr. Professor of Pathology & Biology of Aging, University of Washington
Advised on NOVOS Core Clinical formulation

Longevity Tools Backed by Science

novos life app homepage

Track your biological age, receive personalized protocols, and optimize your daily habits with AI guidance.

NOVOS Life
https://novoslabs.com/wp-content/themes/ageless/assets/img/apple-store.svg
https://novoslabs.com/wp-content/themes/ageless/assets/img/google-play.svg
novos flow blog home

In-depth articles translating longevity science into practical action.

NOVOS Flow
novos longevity diet home

Science-informed nutrition strategies that support metabolic and cellular health.

NOVOS Diet
novos longevity regimen home

Step-by-step protocols for supplements, training, and lifestyle habits that support healthy aging.

NOVOS Regimen
novos recommended usage

AI-powered facial age analysis that estimates biological facial age and tracks progress over time.

NOVOS FaceAge
novos life app homepage

Track your biological age, receive personalized protocols, and optimize your daily habits with AI guidance.

NOVOS Life
https://novoslabs.com/wp-content/themes/ageless/assets/img/apple-store.svg
https://novoslabs.com/wp-content/themes/ageless/assets/img/google-play.svg
novos flow blog home

In-depth articles translating longevity science into practical action.

NOVOS Flow
novos longevity diet home

Science-informed nutrition strategies that support metabolic and cellular health.

NOVOS Diet
novos longevity regimen home

Step-by-step protocols for supplements, training, and lifestyle habits that support healthy aging.

NOVOS Regimen
novos recommended usage

AI-powered facial age analysis that estimates biological facial age and tracks progress over time.

NOVOS FaceAge

Everything You Need for Longevity

$79 / box
NOVOS Core

NOVOS Core

All-In-One Longevity System. Our clinically studied foundational daily formulation supporting whole-body health at the system level.

$43.20 / box
NOVOS Bar

NOVOS Bar

Daily Longevity Bar. The first longevity bar with up to 20 superfoods, built in supplements, and complete nutrition backed by lifespan research.

$49 / pouch
NOVOS Vital

NOVOS Vital

Daily Organ Support Chews. Targeted nutrients to support essential organs including brain, eyes, liver, kidneys, and gut.

$32 / bottle
NOVOS Boost

NOVOS Boost

NAD+ Support Formula. Formulated with NMN to support cellular energy production, metabolic health, and DNA maintenance.

$299 / kit
NOVOS Age

NOVOS Age

Biological Age Test. Measure how your lifestyle is impacting your biology with an at-home epigenetic aging test.

Start With What’s Clinically Studied

NOVOS Core Clinical is our most researched formulation, the foundation of the NOVOS longevity system, and one of the most powerful clinically studied supplements to date.

Not Sure Where To Start?

*These statements have not been evaluated by the Food and Drug Administration. The NOVOS ecosystem is not intended to diagnose, treat, cure, or prevent any disease.

Questions, answered.

Longevity supplements are formulations designed to support healthy aging by targeting biological processes that influence how your body ages. NOVOS supplements use ingredients shown in scientific research to support cellular energy, metabolic health, mitochondrial function, genomic stability, and long-term organ health. They work by providing nutrients your body uses to maintain healthier, more resilient cells as you age.

NOVOS formulations are created specifically to support healthy aging using research-backed ingredients that work together rather than in isolation. Unlike general multivitamins, NOVOS focuses on the biological processes associated with aging, combining supplements, testing, and education to help you make measurable progress over time.

NOVOS products are formulated using well-studied ingredients and responsible dosing. While many people take NOVOS alongside their daily routine, you should always consult your healthcare provider if you are pregnant, breastfeeding, taking medication, or have a medical condition. NOVOS products are not intended to diagnose, treat, cure, or prevent disease.

All NOVOS ingredients are permitted for use in dietary supplements under FDA regulations and meet the safety standards required for over-the-counter use.

For most people, NOVOS Core is the best place to start. It’s the foundational daily mix that targets all 12 causes of aging in one drink, and is designed for early-adult, middle-aged and older adults who want a simple, science-backed anti-aging supplement. Once you’re consistent with Core, you can layer in NOVOS Boost for extra NAD+ support, NOVOS Vital for organ-focused longevity gummies, and NOVOS Bar as a complete longevity nutrition bar that fits into your routine.

Early benefits, such as improved energy, focus, or recovery, often appear within weeks. Customer data shows 81% report improvements in skin, mood, energy, or sleep within two weeks of starting NOVOS Core.

Biological aging changes develop more gradually, with the most significant results emerging after consistent daily use over several months.

NOVOS Age is an advanced biological aging test that uses leading epigenetic algorithms like the DunedinPACE (Columbia & Duke) and Organ Age (Yale) to measure your biological age, the age of key organ systems, and the pace at which you’re aging. This gives you a baseline and helps you track improvements over time as you implement longevity-focused habits and supplements.

Yes. While you can’t change the number of birthdays that have passed (chronological age), it is possible to slow down or accelerate your biological age based upon lifestyle changes.

NOVOS is often taken alongside multivitamins or specific health supplements, but it’s important to review overlapping ingredients and total dosages. If you use prescription medications or have concerns about combining products, you should speak with a qualified healthcare professional.

For the best experience, take NOVOS products as directed. Taking your supplements consistently and pairing them with supportive habits like sleep, nutrition, and movement will help maximise long-term benefits.

NOVOS is designed for adults who want to proactively support healthy aging and take a science-led approach to longevity. Whether you’re already focused on wellbeing or just beginning to explore anti-aging supplements, NOVOS provides a structured system to help you progress in a measurable way.

Yes. We ship NOVOS Core, NOVOS Boost, NOVOS Vital and NOVOS Bars to many countries. Currently, NOVOS Age is only available in the United States. International shipping usually takes 7–10 business days, depending on location, customs and time of year. Read more about our shipping policy.

Unopened U.S. orders can be returned within 30 days and include a prepaid return label (shipping and restocking fees apply unless you choose store credit). International orders are final sale. Damaged or defective items must be reported within 2 days of delivery for replacement. Read more about our return policy.

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