Using nature-based ingredients shown to address aging from the inside out
Most anti-aging companies lack understanding of what causes aging. At best, they may address signs of aging, without impacting underlying causes.
NOVOS is the only company to target the 12 causes of aging using multiple ingredients – an approach backed by top scientists.
What happens in your body that leads to the problems of aging? Latest research uncovered 10 key mechanisms.
During aging, mitochondria – the power plants of our cells – become dysfunctional.
Addressed by
Malate | Glycine
Alpha-ketoglutarate | Fisetin
Glucosamine | Vitamin C
Pterostilbene
Senescent cells are former healthy cells that stopped dividing and secrete substances that damage healthy surrounding cells.
Addressed by
Fisetin
Over time, more and more proteins accumulate inside and outside our cells, interfering with their proper functioning.
Addressed by
Lithium | Glycine
Glucosamine | Fisetin
When we get older, our cells become increasingly exposed to a hostile environment, characterized by inflammation, senescent cells, dysfunctional stem cells, and deleterious substances.
Addressed by
Ginger | Fisetin
Glucosamine
During aging, our DNA becomes damaged, and telomeres become shorter and dysfunctional, especially in stem cells and fast-dividing cells.
Addressed by
Pterostilbene | Glucosamine
Magnesium
During aging, the epigenome – the molecular machinery that regulates our genes’ activity – becomes disorganized.
Addressed by
Lithium | Glycine
Alpha-ketoglutarate | Vitamin C
Ginger | Pterostilbene
As we age, the ends of DNA, known as telomeres, get shorter and cannot protect DNA any longer.
Addressed by
Lithium | Magnesium
Pterostilbene
During aging, our cells become less tuned to nutrient signals, which disrupts a cell’s ability to produce energy.
Addressed by
Fisetin | Pterostilbene
With age, stem cells become dysfunctional or die off, leading to our tissues being less replenished & maintained.
Addressed by
Glycine | Alpha-ketoglutarate
As we grow older, sugar-derived bonds, or crosslinks, are formed between the proteins that make up our tissues, making tissues more stiff.
Addressed by
Glycine | L-Theanine | Alpha-ketoglutarate
NOVOS and its team of expert scientists and medical doctors poured through research to select the most promising longevity ingredients.
Glycine has shown to extend lifespan in different species. In humans, higher glycine levels are associated with heart health, combating inflammaging at the cellular level, and supporting glucose metabolism.
Alpha-ketoglutarate (AKG) extends lifespan and healthspan in different species. In humans, alpha-ketoglutarate has shown to protect cells against damage and stressors. Alpha-ketoglutarate supports a healthy metabolism and a healthy epigenome.
Rhodiola extends lifespan in different species. Substances in Rhodiola, like salidroside, have shown to support nerve regeneration in animals, normal sirtuin and AMPK function in human cells, and help the body to manage senescent cells.
Large studies found that people who take glucosamine live longer. Glucosamine intake was also associated with better heart health. In animals, glucosamine extends lifespan. Glucosamine targets inflammaging at the cellular level, and helps the body to manage oxidative stress and support autophagy.
Vitamin C can help to maintain a proper epigenome, especially in combination with another longevity ingredient, alpha- ketoglutarate.
Pterostilbene, a natural substance found in blueberries, is better absorbable and lasts longer in the body than resveratrol, a compound that has shown to extend lifespan in different species. Pterostilbene can target inflammaging at a cellular level and contribute to a healthy epigenome and DNA stability.
Fisetin has shown to extend lifespan in animals. Fisetin helps the body to manage senescent cells, and can combat inflammaging at the cellular level.
Various studies found that people who take micro doses of lithium live longer. In human studies, supplementing with microdosed lithium supports healthy brain aging. Micro doses of lithium extend lifespan in multiple species.
Ginger can protect cells against damage and has various longevity-promoting effects. In humans, ginger can target inflammaging at a cellular level, can help to maintain proper glucose levels and support a healthy metabolism, and help to mitigate oxidative damage in cells
Malate is a natural substance found in apples which has shown to extend lifespan in organisms. Malate can support healthy energy levels in humans.
People who supplement with magnesium have shown to have less DNA damage. Magnesium supports a healthy metabolism and targets inflammation at the cellular level.
Hyaluronic acid can reduce the appearance of wrinkles when taken orally. A component of hyaluronic acid, acetyl-glucosamine, has shown to extend lifespan in animals.
Theanine is one of the substances responsible for the healthy effects of green tea. Theanine can extend lifespan in different organisms. It can upregulate aging-protective proteins, like FOXO1 and antioxidative enzymes and can help the body to manage crosslinks.
In humans, nicotinamide mononucleotide (NMN) increases levels of NAD+, which is needed for proper DNA repair and to maintain the epigenome. NMN has shown to support a healthy metabolism in humans, and improve muscle strength and performance in the elderly. In animals, NMN slows down various aging processes.
NOVOS and its team of scientists & medical doctors continually perform thorough research to select the best ingredients in longevity.
We follow up with the latest scientific studies and findings in the aging field to constantly improve our products.
We meet on a regular basis with the world’s leading aging scientists. In fact, several are on our scientific advisory board.
We realize that aging is a complex phenomenon needing ingredients to impact multiple aging pathways synergistically.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
