01
A Systems Approach to Aging
Designed around all 12 Hallmarks of Aging, not a single pathway, ingredient, or trend.
Aging is complex.
It’s driven by 12 interconnected biological mechanisms.
No single ingredient can meaningfully address all of them.
That’s why formulation & testing matters.
8 yrs
of research
7
scientists & MDs
7
whole formulation studies
400+
ingredient studies
2,000+
verified clinicians recommend
3rd
party-tested for purity & potency
Why NOVOS Is
Scientifically Different
We pioneered the first formulation designed to address all 12 Hallmarks of Aging simultaneously, with scientific studies at universities around the world.
02
The Complete Formula Is Studied
Most supplements rely on research about individual ingredients. NOVOS studies the complete Core formulation people actually take, because ingredients can behave differently when combined.
03
From Mechanisms to Human Trials
Our research spans cellular mechanisms, animal lifespan, epigenetic aging, and randomized, double-blind, placebo-controlled human research.
04
Built With Leading Longevity Scientists
Developed with internationally recognized scientists and physicians working across the biology of aging.
05
Recognized and Trusted Worldwide
Selected by leading longevity organizations and trusted by major hospitals, clinics, and more than 2,000 healthcare professionals.
More good years,
& the science to back it up
Studies conducted by scientists and physicians at universities worldwide have found that NOVOS formulations produce a range of longevity-relevant outcomes.
Cardiovascular health is longevity
Cardiovascular disease is the leading cause of age-related death worldwide, while better cardiovascular health is associated with substantially longer life expectancy. Healthy blood vessels are central to both lifespan and healthspan.
- Conducted at
- University of Surrey
- Conducted by
- Christian Heiss, MD
- Professor of Cardiovascular Medicine, Associate Head of Medical School
The human trial
In a randomized, double-blind, placebo-controlled trial of healthy adults ages 40 to 65, NOVOS Core demonstrated both immediate and sustained improvements in cardiovascular markers, with effects observed after the first dose and at six months.
NOVOS Core showed greater improvements in cardiovascular health markers than most studied supplements & lifestyle changes
The improvements observed in the study were larger than those reported in several published studies of commonly researched cardiovascular interventions.
Sustained FMD benefit (%)
PWV benefit (m/s)
SBP benefit (mmHg), for blood pressure already in normal range
Based on a comprehensive analysis of comparable published studies across endothelial function, arterial flexibility, and blood pressure. Comparisons were not from head-to-head trials.
Biotech standards applied to natural supplements
Three levels of scientific study
- In Vitro Mechanisms of Aging
- Animal Lifespan
- Human Healthspan & Surrogates of Aging
Study highlights
77%
DNA protection in vitro
Ingredients in NOVOS Core supported DNA integrity by up to 77% in skin cells exposed to irradiation.
In vitro study. Not indicative of human outcomes.
18%
Longer lifespan animal
In aged mice, NOVOS Core extended lifespan by over 18%.
Animal study. Results may not translate to humans.
73%
Aged slower case study
In a 12-participant case study, 73% slowed their biological pace of aging.
Case study, n=12. Individual results may vary.
22%
Firmer skin pilot
In a 6-month pilot, all participants improved skin firmness by an average of 22%.
Pilot study, n=4. Individual results may vary.
Built With World-Class Scientists
“NOVOS has been using a novel science-based approach for developing its formulation. [They are] a leader in the longevity space.”
Dr. J. Pedro Magalhães, PhD
Harvard Medical School
“I see NOVOS as inspiring: they approach aging as a complex phenomenon, aiming at all pathways and Hallmarks of Aging simultaneously.”
Dr. George Church, PhD
Harvard Medical School
“What really impressed me about NOVOS was the comprehensiveness of their analysis of aging research to design their product.”
Dr. Pamela Maher, PhD
Salk Institute
“NOVOS Core has been reviewed by scientists within the aging research community to ensure the most effective and safest ingredients.”
Dr. Oliver Medvedik, PhD
Harvard Medical School, The Cooper Union
No Other Longevity Company Comes Close
Feature
NOVOS
Most others
NOVOS studies the complete formulation rather than assuming that findings from individual ingredients will apply to the finished product, as ingredient-level results often do not translate to the formula as a whole. This allows researchers to evaluate the actual combination, doses, and effects customers receive.
Yes
Ingredient studies only
NOVOS Core was evaluated in randomized, double-blind, placebo-controlled human clinical research—the gold standard scientific design used to reduce bias and compare outcomes against placebo. Findings are now under peer review.
Yes
Rarely
The NOVOS research program spans cellular models, animal research, and human clinical research. Each level answers a different question—from biological activity and effects on aging mechanisms, to organism-level lifespan outcomes, to measurable effects on biological systems predictive of healthspan and lifespan in people.
Yes
Rarely across all three
In a randomized, double-blind, placebo-controlled human trial, the complete NOVOS Core formulation provided nutritional support for biological systems predictive of lifespan and healthspan. The trial included clinically recognized measures of vascular aging and cardiovascular function.
Yes
Extremely rare
The complete NOVOS Core formulation was evaluated in an animal lifespan study and increased lifespan by more than 18% compared with the control group, the largest percentage increase we identified among studies of aged mice. Animal studies do not demonstrate that the formulation extends human lifespan and are not relied upon to represent health benefits in humans.
Yes
Almost never
The human trial measured endothelial function, blood-vessel flexibility, and systolic blood pressure already within the normal range. These are objective functional measures of how the cardiovascular system is working, rather than customer surveys, subjective reports, or surrogate blood biomarkers.
Yes
Often surveys, not measures
Tested, verified,
& transparent.
Every batch is held to the same standard the science demands: independently checked and openly documented.
- Independently tested by Light Labs Third-party laboratory analysis, separate from NOVOS.
- Verified on SuppCo Listed and verified on the independent supplement transparency platform.
- Certificate of Analysis on every batch A documented CoA accompanies each production run.
Recognized across science,
beauty & innovation.
Honored by influential organizations and publications shaping longevity, wellness, skin health, and the future of business.
-
WSJ Future of Everything
- XPRIZE Top 100 Projects Healthspan Competition
- Beacon Awards
- BeautyMatter Future 50
- Beauty From Within category
- INNOCOS Wellness & Longevity Choice Awards
Build your longevity routine
Start with comprehensive daily support. Add targeted nutrition, energy, and measurement based on your goals.
Start here
NOVOS Core
12 Hallmarks One daily drink Human clinical trial
Comprehensive daily support for energy, sleep, focus, and whole-body resilience—targeting all 12 Hallmarks of Aging.
From $2.60/day.Start with Core
NOVOS Boost
99% pure NMN NAD+ support Pairs with Core
Targeted support for cellular energy, healthy metabolism, and staying strong as you age.
From $1.05/day.Shop Boost
NOVOS Vital
7 organ systems Daily gummies Clinically studied
Daily support for seven key organ systems, with clinically studied ingredients for cardiovascular and whole-body health.
From $1.63/day.Shop Vital
NOVOS Bar
15g protein 7g fiber Up to 20 superfoods
Protein, fiber, superfoods, and key longevity nutrients for the days a full meal is hard to get to.
$3.60 per bar with subscription.Shop Bar
NOVOS Age
One blood sample 4 age metrics Lab-grade
See how you are aging with Biological Age, Pace of Aging, Organ Ages, and Telomere Length—all from one blood sample.
$349 single kit.Shop AgeQuestions, answered.
Everything you need to know about NOVOS, the science, and getting started.
What is NOVOS Core?
A once-daily drink with 12 science-backed ingredients, uniquely designed to address all 12 Hallmarks of Aging simultaneously. One sachet mixes into water, juice or a smoothie, in Orange, Tropical Passion or Unflavored.
Shop NOVOS Core What makes NOVOS different from other longevity supplements?
Most companies sell supplements. NOVOS studied its finished formula in a randomized, double-blind, placebo-controlled human clinical trial, then built the tools to let you measure your own progress.
Read the clinical studyIs NOVOS backed by human clinical research?
Yes. NOVOS Core was studied in a randomized, double-blind, placebo-controlled trial at the University of Surrey, where adults 40+ took one serving daily for six months.
See clinical results How soon might I notice a difference?
Timelines vary from person to person. Some notice steadier energy or sleep in the first weeks, and in a self-reported customer survey 81% of NOVOS customers feel a difference within 2 weeks across areas like skin, energy, mood, cognition, sleep and overall well-being. Changes in aging biology build over time, which is why the clinical study ran for six months. Self-reported. Individual results will vary.
Start with NOVOS Core Which NOVOS product should I start with?
Most people start with NOVOS Core as the daily foundation, then add NOVOS Boost or NOVOS Vital depending on their goals. NOVOS Bar is the on-the-go option, with 20+ longevity ingredients and 15 g of protein. NOVOS Age lets you measure where you are and track your progress.
Explore NOVOS Bar How can I measure my progress?
NOVOS Age measures your Biological Age, Pace of Aging, Organ Ages, and Telomere Length from a single blood sample, so you can track changes over time.
Shop NOVOS Age Have more questions? Click here for our FAQ page.