NOVOS Core is made of 12 natural, FDA-approved ingredients that synergistically target 12 causes of aging. This approach is backed by our team of longevity experts from Harvard, MIT, and more. See each ingredient below, including the role each plays in longevity and the science behind them.
NOVOS Evidence
NOVOS Core is the first formula to address aging by targeting the 12 fundamental causes of aging.
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NOVOS Core
Fisetin has shown to extend lifespan in animals. Fisetin helps the body to manage senescent cells, and can combat inflammaging at the cellular level.
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NOVOS Core
Glycine has shown to extend lifespan in different species. In humans, higher glycine levels are associated with heart health, combating inflammaging at the cellular level, and supporting glucose metabolism.
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NOVOS Core
Pterostilbene, a natural substance found in blueberries, is better absorbable and lasts longer in the body than resveratrol, a compound that has shown to extend lifespan in different species. Pterostilbene can target inflammaging at a cellular level and contribute to a healthy epigenome and DNA stability.
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NOVOS Core
Rhodiola extends lifespan in different species. Substances in Rhodiola, like salidroside, have shown to support nerve regeneration in animals, normal sirtuin and AMPK function in human cells, and help the body to manage senescent cells.
Learn more about Rhodiola Rosea
NOVOS Core
Various studies found that people who take micro doses of lithium live longer. In human studies, supplementing with micro-dosed lithium supports healthy brain aging. Micro doses of lithium extend lifespan in multiple species.
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NOVOS Core
Alpha-ketoglutarate (AKG) extends lifespan and healthspan in different species. In humans, alpha-ketoglutarate has shown to protect cells against damage and stressors. Alpha-ketoglutarate supports a healthy metabolism and a healthy epigenome.
Learn more about Calcium Alpha-Ketoglutarate
NOVOS Core
Malate is a natural substance found in apples which has shown to extend lifespan in organisms. Malate can support healthy energy levels in humans. Note: Malate and Magnesium come together as Mg Malate.
Learn more about Malate (as Magnesium Malate)
NOVOS Core
Glucosamine can help to lower aging-related low-grade inflammation (inflammaging) and can extend lifespan in various organisms. It can also mimic a calorie-restricted diet and induce the formation of new mitochondria.
Learn more about Glucosamine Sulfate
NOVOS Core
People who supplement with magnesium have shown to have less DNA damage. Magnesium supports a healthy metabolism and targets inflammation at the cellular level. Note: Malate and Magnesium come together as Mg Malate.
Learn more about Magnesium (as Magnesium Malate)
NOVOS Core
Hyaluronic acid can reduce the appearance of wrinkles when taken orally. A component of hyaluronic acid, acetyl-glucosamine, has shown to extend lifespan in animals.
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NOVOS Core
Theanine is one of the substances responsible for the healthy effects of green tea. Theanine can extend lifespan in different organisms. It can increase the production of aging-protective proteins, like FOXO1 and antioxidative enzymes and can help the body to manage crosslinks.
Learn more about L-Theanine
NOVOS Core
Vitamin C can help to maintain a proper epigenome, especially in combination with another longevity ingredient, alpha-ketoglutarate.
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NOVOS Core
Ginger can protect cells against damage and has various longevity-promoting effects. In humans, ginger can target inflammaging at a cellular level, can help to maintain proper glucose levels and support a healthy metabolism, and help to mitigate oxidative damage in cells
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NOVOS Boost
In humans, nicotinamide mononucleotide (NMN) increases levels of NAD+, which is needed for proper DNA repair and to maintain the epigenome. NMN has shown to support a healthy metabolism in humans, and improve muscle strength and performance in the elderly. In animals, NMN slows down various aging processes.
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NOVOS Vital
Trehalose, a natural sugar, enhances organ health by promoting cellular cleansing, reducing inflammation, and supporting brain, liver, and kidney function.
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NOVOS Vital
Apple cider vinegar, derived from fermented apple juice, is rich in nutrients and boosts metabolic health, and supports brain, kidney, and cardiovascular functions.
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NOVOS Vital
Nattokinase, an enzyme from Japanese fermented Natto rich in vital nutrients like iron and vitamins, promotes cardiovascular and brain health.
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NOVOS Vital
Rutin, a phytonutrient found in foods like buckwheat and cherries, supports healthy aging, enhances metabolic health, and maintains muscle health during aging.
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NOVOS Vital
Lutein, a carotenoid in fruits and vegetables, concentrates in the retina and offers antioxidant benefits, aiding in eye health maintenance and cognitive function.
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NOVOS Vital
Zeaxanthin, a carotenoid found in foods like carrots and salmon, provides antioxidant benefits and supports eye health, aiding in cognitive function and delaying brain aging in adults.
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NOVOS Vital
Inulin, a dietary fiber found in various fruits and vegetables, acts as a prebiotic to enhance gut health, supports digestion and metabolism, and positively influences the gut microbiome's composition.
Learn more about Inulin
NOVOS Bar
Taurine is a powerhouse nutrient that supports nearly every major system in the body. It boosts mitochondrial energy, optimizes metabolism, reduces inflammation, and supports heart health.
NOVOS Bar
Astaxanthin is a potent antioxidant that supports longevity by reducing oxidative stress, improving skin, boosting immunity, balancing cholesterol, and extending lifespan in male mice.
NOVOS Bar
Mushrooms are adaptogens that support brain function, immunity, energy, and stress response. They enhance cognition, boost mitochondria, and reduce oxidative stress.
NOVOS Bar
The Fruit and Veggie Blend in NOVOS Bar fills common nutrient gaps with food-based antioxidants and micronutrients that support mitochondria, DNA repair, immunity, and healthy aging.
NOVOS Bar
Seeds are nutrient-dense sources of essential fats, antioxidants, and minerals that support mitochondria and immunity. They help improve metabolism, reduce inflammation, and promote healthy aging.
NOVOS Bar
Protein supports metabolism, muscle maintenance, and cellular health. It regulates aging pathways like mTOR and IGF-1, helping control inflammation, glucose, and longevity.
NOVOS Bar
Honey is a bioactive-rich sweetener that supports metabolism, reduces inflammation, and improves lipid and glucose levels.
NOVOS Bar
Olive oil supports heart, brain, and metabolic health while reducing inflammation and oxidative stress, which is key to healthy aging.
NOVOS Bar
Sunflower lecithin supports healthy aging by strengthening cell membranes, boosting cognition, reducing inflammation, and aiding metabolism.
NOVOS Bar
Cocoa is rich in polyphenols that support heart, brain, and metabolic health. It improves blood flow, lowers inflammation, and regulates glucose and lipids.
