Sleep + Healthy Aging
Better nights.
More restored mornings.
Sleep is more than hours in bed. It is falling asleep, staying asleep, moving through restorative sleep stages, and waking recharged for the day.
NOVOS supports calm, restful sleep, sleep quality, and next-day recovery through ingredients backed by human research, without building your routine around sedatives.
Sleep-related evidence comes primarily from human studies of individual ingredients. The finished NOVOS Core formula has been clinically studied for cardiovascular benefits.
2,000+
Verified clinicians recommend
15M+
NOVOS servings enjoyed
81%
Feel a difference after 2 weeks*
8
Years of R&D behind NOVOS Core
*Based on a self-reported customer survey across six areas of daily wellbeing: sleep, mood, cognition, energy, skin, and overall wellbeing. This does not mean that 81% specifically reported better sleep. Individual results vary.
Sleep is a system
Eight hours asleep does not always mean eight hours restored.
Falling asleep is only one part of a good night. Staying asleep, completing enough sleep cycles, waking at the right time, and feeling restored the next morning matter too.
Selected pattern
Falling asleep
You are tired, but your body and mind have not completed the transition into sleep. Timing, light, caffeine, stress, and relaxation all matter.
Staying asleep
You fall asleep normally, but repeated awakenings fragment the night and can leave sleep feeling less restorative.
Waking too early
You wake before your intended time and cannot return to sleep, shortening the later part of the night when REM sleep becomes more prominent.
Not enough total sleep
No supplement can replace hours that were never available for sleep. Time in bed remains the foundation.
Deep or REM concerns
Sleep stages cycle throughout the night. Deep sleep is concentrated earlier, while REM becomes more prominent later. Consumer wearables estimate these stages; they do not measure them like a sleep laboratory.
Waking unrefreshed
You may have slept for seven or eight hours but still wake foggy or depleted. Sleep quality and next-day restoration matter alongside duration.
Better sleep begins by identifying which part of the night is actually going wrong.
A night is a sequence — not one continuous state.
Conceptual illustration of normal sleep architecture. Tap a stage to learn more.
Brief awakenings can occur between cycles and do not always mean the whole night was poor.
N1 is the light transition into sleep.
N2 is a lighter non-REM sleep stage that makes up much of the night.
Deep sleep is generally concentrated earlier in the night and tends to decline with age.
N2 is a lighter non-REM sleep stage that makes up much of the night.
REM periods generally lengthen later in the night.
Brief awakenings can occur between cycles and do not always mean the whole night was poor.
N2 is a lighter non-REM sleep stage that makes up much of the night.
Deep sleep is generally concentrated earlier in the night and tends to decline with age.
N2 is a lighter non-REM sleep stage that makes up much of the night.
REM periods generally lengthen later in the night.
N2 is a lighter non-REM sleep stage that makes up much of the night.
REM periods generally lengthen later in the night.
Brief awakenings can occur between cycles and do not always mean the whole night was poor.
Deep sleep
Slow-wave sleep is typically concentrated earlier in the night and tends to decline with age.
REM sleep
REM periods generally lengthen later in the night, which is one reason repeatedly cutting sleep short matters.
Wearable data
Use wearables to identify trends over time, not to grade a single night.
Beyond the night
Sleep supports healthy aging across the body.
Brain + cognition
Sleep supports memory consolidation, learning, attention, and emotional regulation. Long-term observational research also connects persistently short or disrupted sleep with poorer cognitive outcomes later in life.
Heart + circulation
Healthy sleep supports normal blood-pressure regulation, autonomic balance, glucose metabolism, and vascular function. Short and disrupted sleep are consistently associated with poorer cardiovascular health.
Metabolism + immunity
Sleep helps regulate glucose handling, appetite signals, stress responses, and immune activity — interconnected systems that influence energy, resilience, and healthy aging.
Recovery + readiness
During sleep, the body coordinates processes involved in tissue recovery, exercise adaptation, and physical restoration. Better-quality sleep also supports next-day mental and physical readiness.
The NOVOS approach
Two products. Two distinct sleep-support roles.
NOVOS does not approach sleep as a knockout effect. Core provides the broadest sleep-support foundation. Boost adds focused NMN support for people who also want to support NAD+, cellular energy, and daytime function.
NOVOS products support normal structure and function. They have not been shown to prevent or reduce the risk of dementia, cardiovascular disease, cancer, or any other disease.
NOVOS Core
Calm, restful sleep inside a complete longevity formula.
- Glycine
- L-Theanine
- Magnesium
- Rhodiola, for stress resilience
- Relaxation + restful sleep
- Next-morning recovery
NOVOS Boost
Focused NMN support for sleep quality and daytime energy.
- NMN
- NAD+ support
- Human ingredient research
- Sleep quality
- Daytime drowsiness
These products are complementary, not interchangeable. If sleep is the primary goal, start with Core.
The foundation
NOVOS Core supports sleep without acting like a sleeping pill.
Core is a once-daily longevity formula designed around the biological systems that change with age. Within its broader 12-ingredient formula are ingredients with direct human research related to sleep, relaxation, and stress resilience.
Together, they support a calmer transition into sleep, restful sleep quality, and how restored you feel the following morning.
2,000 mg Glycine
Sleep quality + next-morning research
150 mg L-Theanine
Relaxation + human sleep research
304 mg Magnesium
As Magnesium Malate
No proprietary blend. Every ingredient and amount is disclosed.
What the human research found.
Support for sleep quality—and the morning after.
In controlled human studies, Glycine was associated with better subjective sleep quality, shorter time to fall asleep, shorter time to reach slow-wave sleep, and improvements in next-morning fatigue, liveliness, and clear-headedness.
A calmer path into restful sleep.
A 2025 systematic review and meta-analysis of 19 randomized-trial articles involving 897 participants found significant pooled improvements in subjective sleep-onset latency, daytime dysfunction, and overall subjective sleep quality.
Foundational support, with more mixed sleep evidence.
Magnesium is essential for normal nervous-system and muscle function. Human trials and systematic reviews have reported sleep-related benefits, including shorter sleep-onset latency and modest improvements in insomnia-severity scores.
Side by side
Core vs. Boost
| NOVOS Core | NOVOS Boost | |
|---|---|---|
| Primary role | Foundational longevity + sleep support | Focused NMN + NAD+ support |
| Sleep position | Primary NOVOS sleep-support product | Complementary |
| Key sleep-relevant ingredients | Glycine, L-Theanine, Magnesium | NMN |
| Research type | Human studies of individual ingredients | Human studies of NMN |
| Finished product tested for sleep? | No | No |
| Other major benefits | Whole-body healthy aging, cardiovascular support, energy, skin | Cellular energy, NAD+, metabolic and cellular maintenance |
| Format | Once-daily drink mix | Capsules |
| Contains melatonin? | No | No |
| Contains stimulants? | No | No |
| Best starting point | Most people approaching NOVOS for sleep | People specifically seeking NMN/NAD+ support |
What customers say
Real routines, real reports.
“What I notice the most is that I AM SLEEPING BETTER!! I'm 75 and always get up to go to the bathroom, but now I get back to sleep with relative ease. That's a huge benefit.”
“So far so good. I am almost one month in using NOVOS Core and Boost. I sleep well and wake up refreshed. My energy has also increased.”
“I've been using NOVOS Core for 4 weeks every day. I definitely have more energy and I feel that my sleep quality is noticeably better.”
“I've been taking NOVOS Core for almost one month now. I wake up refreshed (taking NOVOS Core right before bed), with energy, and even noticed my mind is sharper.”
“I have been taking Boost for over 1yr and noticed a rise in my energy after only a few months, then a healthy change in my immune system, quality of sleep and overall appearance.”
“Me, 44yrs and my partner 56yrs have been taking core three times a week + boost 5 times a week for two yrs now. We always have the energy to use our home gym each morning.”
“I'm coming up on my first month of core + boost — and it's really already changing my energy levels. I just feel BETTER.”
The research
Every claim traces to a source.
Meta-analysis of quantitative sleep parameters from childhood to old age in healthy individuals.
Ohayon MM, et al. Sleep, 2004;27(7):1255-1273
Supports: Age-related changes in total sleep, sleep efficiency, nighttime wakefulness, slow-wave sleep, and REM.
Limitations: Population-level normative analysis; not a NOVOS study.
Performance of consumer wrist-worn sleep tracking devices compared to polysomnography: a meta-analysis.
Lee YJ, et al. J Clin Sleep Med, 2025;21(3):573-582
Supports: Differences between consumer sleep trackers and polysomnography for sleep time, latency, efficiency, and awakenings.
Limitations: Explains measurement limits; not evidence a product changes sleep stages.
Real-World Use of Consumer Sleep Devices: A Rapid Review.
Landvatter J, et al. CHEST, 2026;169(4):1101-1110
Supports: Wearables are more useful for broad sleep-pattern trends than precise stage or fragmentation measures.
Limitations: Measurement guidance only; not an intervention study.
Subjective effects of glycine ingestion before bedtime on sleep quality.
Inagawa K, et al. Sleep and Biological Rhythms, 2006;4:75-77
Supports: Next-morning fatigue, liveliness, and clear-headedness outcomes in a randomized crossover setting.
Limitations: Ingredient study; not a NOVOS Core trial. Small sample.
Glycine ingestion improves subjective sleep quality in human volunteers, correlating with polysomnographic changes.
Yamadera W, et al. Sleep and Biological Rhythms, 2007;5:126-131
Supports: Subjective sleep quality, sleep efficiency, sleep-onset latency, latency to slow-wave sleep, and daytime outcomes.
Limitations: Small ingredient study. Overall sleep architecture was not significantly altered.
The Effects of Glycine on Subjective Daytime Performance in Partially Sleep-Restricted Healthy Volunteers.
Bannai M, et al. Frontiers in Neurology, 2012;3:61
Supports: Fatigue and psychomotor-vigilance outcomes during experimental partial sleep restriction.
Limitations: Ingredient study; Glycine did not replace missing sleep hours.
The effects of L-Theanine consumption on sleep outcomes: A systematic review and meta-analysis.
Bulman A, et al. Sleep Medicine Reviews, 2025;81:102076
Supports: Significant pooled changes in subjective sleep-onset latency, daytime dysfunction, and overall subjective sleep quality.
Limitations: Not every objective sleep outcome improved consistently; not a finished NOVOS Core trial.
Examining the effect of L-Theanine on sleep: a systematic review of dietary supplementation trials.
Cotter J, et al. Nutritional Neuroscience, 2026;29(2):224-238
Supports: Standalone L-Theanine studies involving sleep latency, maintenance, efficiency, satisfaction, and refreshment.
Limitations: Several authors were affiliated with British American Tobacco Investments; protocols varied.
Oral magnesium supplementation for insomnia in older adults: a systematic review and meta-analysis.
Mah J, Pitre T. BMC Complement Med Ther, 2021;21:125
Supports: Possible reduction in sleep-onset latency in older adults.
Limitations: Underlying evidence was low-to-very-low certainty; not a NOVOS Core study.
Magnesium Bisglycinate Supplementation in Healthy Adults Reporting Poor Sleep: A Randomized, Placebo-Controlled Trial.
Schuster J, et al. Nature and Science of Sleep, 2025;17:2027-2040
Supports: Modest improvement in insomnia-severity scores in adults reporting poor sleep.
Limitations: The intervention was Magnesium Bisglycinate. NOVOS Core contains Magnesium Malate.
Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults.
Kim M, et al. Nutrients, 2022;14(4):755
Supports: Human NMN study assessing sleep quality, fatigue, and physical performance with 250 mg NMN for 12 weeks.
Limitations: Independent NMN study; not a clinical sleep trial of NOVOS Boost. Older Japanese adults.
Research increasingly connects sleep duration, continuity, and quality with long-term cognitive, cardiovascular, metabolic, and overall health. These studies help explain why sleep is an important part of healthy aging; they do not establish that NOVOS products prevent disease.
Association of sleep duration in middle and old age with incidence of dementia.
Sabia S, et al. Nature Communications, 2021;12:2289
Supports: Observational association between persistently short sleep duration in midlife and later life and higher incidence of dementia.
Limitations: Observational cohort research. Shows association, not causation.
Sleep Duration and Quality: Impact on Lifestyle Behaviors and Cardiometabolic Health. A Scientific Statement From the American Heart Association.
St-Onge MP, et al. Circulation, 2016;134(18):e367-e386
Supports: Relationships between sleep duration/quality and cardiometabolic health, including blood pressure, glucose metabolism.
Limitations: Scientific statement synthesizing largely observational evidence.
About Sleep and Sleep Health (general sleep-health resource).
CDC. CDC, 2024
Supports: General public-health guidance on recommended sleep duration and healthy sleep habits.
Limitations: Public-health guidance only; makes no claim about dietary supplements.
Recommended Amount of Sleep for a Healthy Adult: A Joint Consensus Statement.
Watson NF, et al. J Clin Sleep Med, 2015;11(6):591-592
Supports: Healthy adults should regularly obtain at least seven hours of sleep.
Limitations: Guidance for sleep duration; not supplement evidence.
Behavioral and psychological treatments for chronic insomnia disorder in adults: clinical practice guideline.
Edinger JD, et al. J Clin Sleep Med, 2021;17(2):255-262
Supports: CBT-I as a recommended first-line behavioral treatment for chronic insomnia.
Limitations: Clinical guidance; not a NOVOS product study.
The basics still matter
FAQ
Frequently asked questions
How does NOVOS Core support sleep?
NOVOS Core contains Glycine, L-Theanine, and Magnesium—ingredients with human research related to relaxation, sleep onset, subjective sleep quality, and next-morning recovery. Core is designed as a daily longevity formula rather than an acute sleeping pill.
Is NOVOS Core a sedative or melatonin supplement?
No. Core contains no melatonin and is not a sedative. It supports the biological foundation for calm, restful sleep as part of a broader healthy-aging routine.
Has NOVOS Core been clinically tested for sleep?
No. The finished Core formula was tested in a randomized, placebo-controlled human trial measuring cardiovascular-aging markers, not sleep. The sleep rationale comes primarily from human studies of individual Core ingredients and from clearly labeled customer-reported experiences.
Will Core increase my deep sleep or REM sleep?
Individual ingredient studies have examined outcomes including sleep onset, subjective sleep quality, sleep efficiency, and time to reach slow-wave sleep. The evidence does not justify promising that Core will increase a specific number of deep-sleep or REM minutes.
When should I take Core?
Take one serving daily. Most customers use Core in the morning, while some prefer later in the day. Consistency matters more than taking it immediately before bed. Follow the product label.
How does Boost relate to sleep?
Boost provides NMN for focused NAD+ support. Human NMN research has reported improvements in sleep-quality measures and daytime drowsiness. These findings come from studies of NMN, not a clinical sleep trial of NOVOS Boost.
Can I take Core and Boost together?
Yes. Core and Boost have complementary roles: Core is the broad longevity and sleep-support foundation, while Boost provides focused NMN and NAD+ support. Follow the labels and speak with a healthcare professional if you take medication, have a medical condition, are pregnant, or are nursing.
How quickly should I expect a difference?
Some customers report noticing differences within the first few weeks, but responses vary. The 81% customer statistic refers to reported changes across six areas of wellbeing—not sleep alone—and is not a clinical sleep result.
Does supporting better sleep reduce the risk of age-related disease?
Healthy sleep supports cognitive, cardiovascular, metabolic, immune, and restorative functions that matter across the lifespan. However, association does not establish that improving sleep — or taking a sleep-support supplement — will prevent a particular disease. NOVOS products are not intended to diagnose, treat, cure, or prevent disease.
Is NOVOS intended to treat insomnia?
No. NOVOS products are not intended to diagnose, treat, cure, or prevent insomnia or another sleep disorder. Persistent or concerning sleep symptoms should be evaluated by an appropriate healthcare professional.
Start tonight
Better sleep starts with a better foundation.
Start with NOVOS Core. Add Boost if dedicated NMN and NAD+ support belongs in your routine.
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.