Metabolism + Weight Management

Weight loss is only part of the goal.

Healthy weight management is not only about losing weight. It is about losing excess fat while protecting the systems that keep you strong, well fed and functional for decades.

Muscle Energy Nutrition Metabolic health Strength Long term function
A strong, healthy woman mid movement in a bright training studio
01 Food and eating pattern 02 Digestion and satiety signals 03 Blood glucose and nutrient delivery 04 Muscle: where nutrients get used 05 Cells and mitochondria 06 Energy, activity and body composition
Metabolism is a system. Weight is one output of that system.
Formulated with a scientific advisory board Third party tested for purity Published research on the Core formula Vegan, non GMO, no added sugar in Core
Featured in press and specialty retail Transparent labels Evidence graded on every claim

Start where you actually are

A lower number is not automatically a better outcome.

Two people can lose the same amount of weight and end up in completely different places. What you lose, and what you protect while losing it, is the part that matters. Pick the starting point that sounds like your week.

I want to lose fat without losing muscle

I want to lose fat without losing muscle

Protein intake, resistance training and overall nutrition quality decide how much of the weight you lose comes from fat instead of lean tissue.

Bar for protein and nutrition quality, Core for whole body support

I feel hungry all the time

I feel hungry all the time

Satiety is driven by protein, fiber, meal structure and sleep. Food composition changes how full a given number of calories feels.

Bar for protein and fiber, Vital for gut and fiber support

My energy crashes in the afternoon

My energy crashes in the afternoon

Energy availability is shaped by what you eat, how well nutrients are delivered and how efficiently cells produce energy.

Boost for cellular metabolism, Core for daily foundation

My digestion feels off

My digestion feels off

Gut function, fiber intake and the microbiome influence appetite signals and how comfortable a nutrition plan feels day to day.

Vital for gut and metabolic support

I am trying to maintain my weight

I am trying to maintain my weight

Maintenance is its own biological phase. Appetite, energy expenditure and lean mass all shift after weight loss.

Bar and Core for consistency, Vital for gut routine

I want long term metabolic health

I want long term metabolic health

Weight is one output. Cardiovascular health, muscle, sleep, stress resilience and cellular energy production matter for the long run.

Core as the foundation, Boost for cellular metabolism

The core idea

Lose fat. Preserve the machinery.

Weight on a scale is a single number that hides two very different things: fat mass and lean mass. Muscle is metabolically active tissue that uses glucose, carries you through daily life and protects long term function.

  • Protein intake shapes how much lean tissue you keep
  • Resistance training gives muscle a reason to stay
  • Fiber and gut health make a plan livable
  • Nutrient adequacy keeps energy and mood workable
Meta analysis Nutrition evidence
Nutrition evidence
Higher protein intake during energy restriction is consistently associated with retaining more lean mass compared with lower protein intake at the same calorie level. This is nutrition science about protein, not a claim about any NOVOS product.
Resistance training
Combining resistance training with adequate protein is the best supported strategy for shifting the composition of weight lost toward fat rather than lean tissue.
Limitation
Individual response varies with age, training history, sleep, total intake and adherence. Nothing here predicts an individual result.

Composition of weight lost, illustrative

Fat
Lean

This diagram is a teaching illustration of a well described nutrition principle, not measured data and not a NOVOS product result. It is here to show direction, not numbers.

Interactive systems map

Six systems sit between your plate and your body composition.

Select a system to see what it does, why it matters for weight management, and how each NOVOS product relates to it.

Appetite and satiety

How full you feel is not only about how much you eat. Protein and fiber slow eating, add volume and change the signals your gut sends after a meal.

Why it matters. When a plan feels punishing, it usually fails. Food composition is the most practical lever most people have.

NOVOS Core

NOVOS Core

Supporting

NOVOS Vital

NOVOS Vital

Supporting

NOVOS Boost

NOVOS Boost

Indirect

NOVOS Bar

NOVOS Bar

Direct

Roles are qualitative descriptions of what each product is designed for. They are not scores or rankings.

The four product system

Different products. Different metabolic jobs.

NOVOS is not four versions of the same idea. Each product does a specific job, and only one of them is food.

NOVOS Core product packaging

Whole body foundation

NOVOS Core

Core is not a weight loss supplement. It is the daily foundation built for whole body health while you work on body composition.

  • Supports cardiovascular, energy, muscle, sleep and stress resilience pathways
  • Built around healthy aging biology rather than fat loss
  • The finished formula human research concerns cardiovascular aging, not weight loss

Chapter 01 · NOVOS Core

Protect the whole body while you change your body.

Core is the daily foundation. It is built for whole body health: cardiovascular function, energy, muscle, sleep, stress resilience and healthy aging pathways. It is deliberately not positioned as a weight loss supplement.

During weight management, the surrounding systems are the ones most often neglected. Sleep gets shorter, stress goes up, nutrient intake narrows and cardiovascular health drops off the priority list. Core exists for that layer.

Finished product trial Limitation: Not a weight loss claim
Finished formula research
The human research on the finished Core formula concerns cardiovascular aging measures. That trial did not test weight loss, fat loss or glucose control, and we do not present it as weight management evidence.
Ingredient research
Individual Core ingredients have their own literature spanning cellular stress response, mitochondrial function and healthy aging pathways. Ingredient research is not the same as finished product evidence.
Limitation
Core is not intended to cause weight loss, burn fat or treat obesity, and we make no such claim.
NOVOS Core packaging

A few ingredients from the Core formula

Calcium alpha ketoglutarate

Calcium alpha ketoglutarate

A metabolite involved in cellular energy pathways and studied in healthy aging research.

Magnesium malate

Magnesium malate

Magnesium participates in hundreds of enzymatic reactions, including energy metabolism.

Ginger extract

Ginger extract

Contains gingerol, studied for effects on cellular stress responses.

Rhodiola extract

Rhodiola extract

Provides salidroside, associated in research with stress resilience pathways.

NOVOS Vital packaging

Chapter 02 · NOVOS Vital

The gut is part of your metabolic story.

Vital centers on inulin, a fermentable prebiotic fiber, and apple cider vinegar, which supplies acetic acid. Rutin plays a secondary supporting role.

Fermentable fiber feeds gut bacteria, which produce short chain fatty acids. Gut function influences digestion comfort, fullness signals after meals and metabolic pathways that sit alongside body composition.

Human ingredient research Emerging evidence Limitation: Retracted study excluded
Inulin and fiber
Fermentable fibers such as inulin are studied for their effects on gut bacteria and short chain fatty acid production. Higher fiber eating patterns are broadly associated with better dietary quality and greater fullness per calorie.
Apple cider vinegar
Acetic acid has been examined in small metabolic studies. Results are mixed and the overall evidence base is limited rather than conclusive.
Transparency about a widely shared study
A 2024 trial reporting unusually large weight loss with apple cider vinegar was formally retracted in 2025. We do not cite it and we do not use its numbers. Anyone who saw those figures circulating should know they no longer stand.
Limitation
Vital is not intended to prevent glucose spikes, cause weight loss or treat any metabolic condition.

Three of the seven actives in the Vital formula

Vital contains seven active ingredients. The three below are the ones most relevant to the gut and metabolic story on this page, so they are the ones we show here.

Inulin from chicory root

Inulin from chicory root

A fermentable prebiotic fiber that gut bacteria use as fuel.

Acetic acid from apple cider vinegar

Acetic acid from apple cider vinegar

The active organic acid in vinegar, studied in metabolic contexts.

Rutin

Rutin

A supporting flavonoid found in foods such as buckwheat and citrus.

Chapter 03 · NOVOS Boost

Underneath metabolism, there is cellular metabolism.

Boost delivers NMN, a precursor to NAD+. NAD+ is a coenzyme central to how cells convert nutrients into usable energy, and it sits inside nutrient sensing pathways that respond to how you eat and move.

Research on NMN spans cellular metabolism, skeletal muscle biology and insulin sensitivity. This is the layer beneath body composition rather than a lever on the scale.

Human ingredient research Preclinical research Limitation: Not a weight loss ingredient
Human ingredient research
Human NMN work includes insulin sensitivity research in specific populations. That was an ingredient study, not a finished NOVOS Boost trial, and it should not be read as a metabolism trial of Boost.
Muscle and nutrient sensing
NAD+ biology intersects with skeletal muscle function and nutrient sensing pathways, much of which comes from preclinical models.
Limitation
NMN is not established as a weight loss ingredient, and Boost is not intended to cause fat loss.
NOVOS Boost packaging
01

Nutrients in

Food is broken down and delivered to tissues through the bloodstream.

02

Into the cell

Insulin sensitivity influences how readily muscle cells take up glucose.

03

NAD+ dependent steps

NAD+ acts as a coenzyme in the reactions that release energy from nutrients.

04

Mitochondria

Mitochondria produce the energy currency cells use to do work.

05

Usable energy

Energy for movement, recovery and everyday function.

Illustration of glucose moving from a blood vessel into a muscle cell
Nutrient delivery into cells
Illustration of skeletal muscle fibers
Muscle: where much of that energy gets used

Chapter 04 · NOVOS Bar

Weight management is a nutrition problem first.

Weight management happens through food. Bar is portion controlled nutrition built around complete protein, fiber, whole food fats and micronutrient adequacy, with low sugar and functional ingredients.

Think of Bar as a muscle preserving nutritional foundation: a convenient way to get protein and fiber into a day that would otherwise drift toward low nutrient snacking. That is a nutrition role, not a drug effect.

  • Complete protein with a full amino acid profile
  • Fiber for volume, texture and slower eating
  • Whole food fats from nuts, seeds and olive oil
  • Micronutrients from fruit and vegetable sources
  • Low sugar, no ultra processed filler
  • Portion controlled by design
Nutrition evidence Limitation: No appetite or muscle claim
Protein and lean mass
Nutrition research links adequate protein intake during energy restriction with retaining more lean mass. Bar is a convenient source of complete protein within that pattern.
Fiber and fullness
Higher fiber foods generally increase fullness per calorie and slow eating rate. This is food science about fiber rather than a clinical effect of Bar.
Micronutrient adequacy
Restricting intake often narrows the variety of foods eaten, which is where micronutrient gaps appear. Nutrient dense options help close that gap.
Limitation
We do not claim Bar clinically suppresses appetite, preserves muscle on its own, prevents glucose spikes or causes weight loss.
NOVOS Bar packaging
Close up of the NOVOS Bar unwrapped, showing its dense extruded texture with chocolate pieces

What is inside, and why it belongs in a weight management plan

Complete protein

Complete protein

Supplies the amino acids that a muscle preserving nutritional foundation depends on.

Fiber

Fiber

Adds volume and slows eating, which changes how satisfying a portion feels.

Organic olive oil

Organic olive oil

Whole food fat associated with better overall dietary patterns.

Nut and seed butters

Nut and seed butters

Fat, protein and texture from recognizable whole foods.

Fruit and vegetable sources

Fruit and vegetable sources

Micronutrients and polyphenols that support nutritional adequacy.

Functional mushrooms

Functional mushrooms

Functional ingredients included for their traditional and emerging research interest.

Two different biological phases

Losing weight and keeping it off are not the same project.

After weight loss, appetite signaling and energy expenditure shift and the body works to defend its previous weight. Switch phases to see what changes.

Active fat loss

Intake is lower, so quality has to be higher.

  • Protein becomes the priority nutrient, not an afterthought
  • Micronutrient gaps appear as food variety narrows
  • Resistance training gives muscle a reason to stay
  • Hunger is real, and food composition is the practical lever

Maintenance

The biology pushes back, so consistency wins.

  • Appetite signaling and energy expenditure shift after loss
  • Lean mass built or kept now pays off over years
  • Sleep and stress matter as much as any single meal
  • Routines you can repeat beat plans you can only sprint
A man and a woman in workout clothes standing together outdoors after a walk
Both phases are lived by real people over years, not weeks.

We do not claim any NOVOS product prevents weight regain. The point of this section is that maintenance deserves its own plan rather than being treated as the absence of a diet.

Compare

Which product does what, in plain language.

These are qualitative roles, not scores. Direct means the product is designed for that job. Supporting means it contributes. Indirect means it sits further upstream. No Role means there is no meaningful connection to that job.

Qualitative product roles by system
Core Vital Boost Bar
Satiety and appetite Supporting Supporting Indirect Direct
Protein and muscle nutrition Supporting Indirect Supporting Direct
Gut and fiber Supporting Direct No Role Supporting
Cellular metabolism and NAD+ Supporting Indirect Direct Indirect
Nutrient density and micronutrients Direct Supporting Indirect Direct
Whole body health and healthy aging Direct Supporting Supporting Supporting
Daily convenience and consistency Direct Supporting Supporting Direct
See the full product page Core → Vital → Boost → Bar →

Or just pick your goal

Bar first, Core alongside

Lose fat, keep muscle

Prioritize protein and nutrition quality, keep resistance training, and use Core as the whole body foundation so the rest of your health is supported.

Where to start

Most people start with one product, not four.

NOVOS Bar packaging

Weight management nutrition

NOVOS Bar

Complete protein to support a muscle preserving nutritional foundation

NOVOS Vital packaging

Gut and metabolic support

NOVOS Vital

Inulin is a fermentable prebiotic fiber that feeds gut bacteria

NOVOS Boost packaging

NAD+ and cellular metabolism

NOVOS Boost

NAD+ is central to how cells convert nutrients into usable energy

NOVOS Core packaging

Whole body foundation

NOVOS Core

Supports cardiovascular, energy, muscle, sleep and stress resilience pathways

Not sure which one fits your week?

Answer a few questions and get a shortlist instead of a guess.

Find My NOVOS Products

Science transparency

Not all evidence is the same, so we label it.

Every claim on this page carries a badge describing what kind of evidence sits behind it. We do not use numerical product scores, and we do not discuss research doses.

Finished product evidence

Research conducted on a complete NOVOS formula. This is the strongest kind of evidence we can point to, and it only covers what the trial actually measured.

Ingredient research

Studies on a single ingredient, often at a research setting rather than in our formula. Useful context, not proof about the product.

Nutrition evidence

Established food science, such as protein and lean mass or fiber and fullness. It describes how nutrients behave, not what a brand does.

Preclinical research

Cell and animal work. It is where mechanisms are discovered, and it frequently does not translate directly to people.

Emerging evidence

Early, small or mixed human findings. Interesting, worth watching, not settled.

Limitations

Where we say plainly what is not known, what we are not claiming, and where a widely shared study has been retracted.

Scientific advisors

People whose research shapes how we talk about metabolism.

Portrait of Dr. Robert Lufkin

Dr. Robert Lufkin

MD, University of Southern California School of Medicine

Physician and author focused on metabolic health, chronic disease and how everyday nutrition shapes long term outcomes.

Portrait of Dr. Oliver Medvedik

Dr. Oliver Medvedik

PhD, Harvard Medical School, faculty at The Cooper Union

Research spanning cellular metabolism, NAD+ biology and the pathways that respond to how we eat and move.

Portrait of Dr. Diogo Barardo

Dr. Diogo Barardo

PhD, Director of Research and Development, NOVOS

Aging biology research that guides how NOVOS formulates and how carefully it describes evidence.

If you are managing a medical condition, taking prescription medication including GLP-1 medication, pregnant, breastfeeding or under the care of a clinician for weight or metabolic health, talk with your healthcare provider before adding supplements. Nothing on this page is medical advice or a treatment for obesity or any disease.

The full system

Support the body you want to keep.

Core for whole body health. Vital for gut and metabolic pathways. Boost for cellular metabolism and NAD+. Bar for satiety, muscle and nutritional adequacy.

Questions people actually ask

Answers, including the ones that are a no.

Will NOVOS help me lose weight?
No NOVOS product is a weight loss product, and we do not claim any of them cause weight loss or burn fat. What they support is the surrounding system: nutrition quality and protein through Bar, gut and metabolic pathways through Vital, cellular metabolism through Boost, and whole body health through Core. Fat loss itself comes from your overall eating pattern, activity and consistency.
Is Core a metabolism supplement?
Core is a whole body healthy aging foundation. It supports cardiovascular, energy, muscle, sleep and stress resilience pathways. Its finished formula human research concerns cardiovascular aging measures, and that trial did not test weight loss, fat loss or glucose control.
Does apple cider vinegar cause weight loss?
We are deliberately careful here. A widely shared 2024 trial reporting unusually large weight loss with apple cider vinegar was formally retracted in 2025, so we do not use it or its numbers. Acetic acid remains an interesting ingredient studied in metabolic contexts, and the honest summary is that the evidence is limited rather than conclusive.
Can Bar replace a meal?
Bar is portion controlled nutrition with complete protein, fiber, whole food fats and micronutrients. Many people use it as a structured part of a meal or as a high quality option instead of a low nutrient snack. It is food, and we describe it as a muscle preserving nutritional foundation rather than something that clinically suppresses appetite or preserves muscle on its own.
Does NMN affect body weight?
NMN is studied for NAD+ metabolism, nutrient sensing and skeletal muscle biology. Human work includes insulin sensitivity research in specific populations, and that research was on the ingredient rather than on the finished NOVOS Boost formula. NMN is not established as a weight loss ingredient.
Why does muscle matter so much for weight management?
Muscle is metabolically active tissue that uses glucose, supports strength and protects long term function. If a large share of the weight you lose is lean tissue, you can end up lighter and less capable. That is why protein intake and resistance training sit at the center of this page.
Is maintenance really different from losing weight?
Biologically, yes. After weight loss, appetite signaling and energy expenditure shift and the body defends its previous weight. Maintenance rewards consistent protein, nutrient density, sleep and activity rather than short intense pushes.
Do I need all four products?
No. Most people start with one or two based on what is actually getting in their way, whether that is hunger, protein intake, digestion, energy or whole body support. The Product Finder is the fastest way to narrow it down.

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