NOVOS is a science-first longevity biotechnology company building the world’s most rigorously validated system for supporting healthspan and longevity, starting with aging itself.
Aging is the primary driver of decline in health and function, yet most health solutions focus on managing symptoms rather than addressing the biology that causes aging in the first place.
For decades, supplements and wellness products have relied on isolated ingredients, untested combinations, and theoretical benefits, rarely evaluated as complete systems in rigorous studies.
We believed longevity — and you — deserved a different standard.
02
The Approach
A Biology-First Approach
NOVOS was founded to do what consumer health had never done: treat aging as a biological process that can be measured, targeted, and improved.
We design formulations and tools based on the fundamental mechanisms of aging, then validate them through mechanistic studies, preclinical research, and human trials. Not as individual ingredients, but as integrated systems.
03
Our Standards
Standards That Guide Every Decision
Evidence before claims
Biology before trends
Systems before single ingredients
Long-term health over short-term hype
Safety, transparency, and scientific rigor always
These standards guide every decision we make, from research to formulation to education.
04
Proof
Evidence, Not Assumptions
Double-blind, placebo-controlled human clinical researchs
Mechanistic studies with leading research institutions
Animal lifespan and cellular aging research
Patents on multi-ingredient longevity systems
Independently tested for purity and safety
Millions of servings taken across countries, ages, and lifestyles
Our Story
Our founders, driven by personal health journeys and profound scientific expertise, established NOVOS with the determination to address aging at its root.
Chris Mirabile
Founder & CEO
After surviving a brain tumor, Chris Mirabile began questioning why medicine waits for disease instead of protecting health earlier.
That question led him to collaborate with leading scientists from Harvard, MIT, the Salk Institute, and beyond to build NOVOS: a company dedicated to preserving health before decline begins.
What started as a personal journey became a commitment to helping people extend both longevity and quality of life through better science, better tools, and better standards.
Scientific Leadership
Guided by the World’s Leading Aging Scientists
“I see NOVOS as inspiring — they approach aging as a complex phenomenon, aiming at all pathways and hallmarks of aging simultaneously.”
Dr. George Church, PhD — Harvard Medical School & MIT Professor
“NOVOS has been using a novel science-based approach for developing its formulation. [They are] a leader in the longevity space.”
Dr. J. Pedro Magalhães, PhD — Harvard Medical School
“What really impressed me about NOVOS was the comprehensiveness of their analysis of aging research to design their product.”
Dr. Pamela Maher, PhD — Salk Institute & University of British Columbia
“It’s the rigorously-researched, science-backed formulations that set NOVOS apart in the longevity supplements space.”
Dr. Robert Lufkin, MD — USC School of Medicine Professor
Behind every data point is a human story. Countless people across the world now use NOVOS as part of their daily health routine, to feel better today while investing in long-term health.
3 Powerful Formulas. 20 Innovative Ingredients. 500+ Studies. View our growing record of direct and indirect NOVOS studies.
18% Lifespan Extension in Aged Mice
In a recent study of aged mice, NOVOS Core increased lifespan by 18%, surpassing all previously studied supplements in similar research, including NAD+ boosters like nicotinamide riboside.
In just 6 months, 73% of NOVOS Core and NOVOS Boost users experienced a significant reduction in their biological aging pace, with an average slowdown of 8.7% which works out to be 31.75 days younger per year. Nobody’s aging sped up.
Ingredients in NOVOS Core reduced the size of human senescent cells (cells that age and become toxic) by approximately 50% in an in-vitro study, offering effects comparable to a pharmaceutical longevity drug, rapamycin*.
NOVOS Core users ranked (#2, #5, and #7) for lowest rates of aging in a global competition that uses the DunedinPACE algorithm created by Duke and Columbia scientists to measure epigenetic changes.
Ingredients in NOVOS Core were able to prevent DNA damage by up to 77% in skin cells exposed to irradiation (e.g., UV rays) in an in-vitro study. In another human skin cell study, DNA was protected from moderate and high intensity chemo drugs.
NOVOS Core’s ingredients reduced unwanted cell death processes called oxytosis/ferroptosis by 50%, while also reducing cellular inflammation, in an in-vitro human cellular study.
NOVOS, established in 2018, is a pioneer in longevity, reshaping the future of aging and enabling healthier, longer lives.
01
2018
NOVOS is founded. Vision established: target aging biology, not symptoms.
02
2019
First formulations designed with scientific advisors. Early human testing begins.
03
2020
Expanded testing, brand launch, and educational platform created.
04
2021
NOVOS Core and Boost launch to early adopters. First in vitro aging studies completed and show reduced DNA damage.
05
2022
NOVOS Age biological age test launches. Studies show reduced cellular senescence.
06
2023
Case studies show slowed biological aging. Peer-reviewed in vitro study shows reduced DNA damage from chemotherapeutics.
07
2024
NOVOS Core demonstrates ~20% lifespan extension in aged mice, and in vitro study shows reduced ferroptosis and cellular inflammation. NOVOS Vital is launched.
08
2025
Launch of the world's first longevity bar. NOVOS enters Mayo Clinic retail.
09
2026
Completion of double-blind, placebo-controlled human clinical research validating NOVOS Core as a complete system.
The product that pioneered the science-based longevity movement.
NOVOS is a Public Benefit Corporation, legally committed to balancing profit with purpose: advancing human health, longevity research, and public education alongside commercial success.
We donate a portion of profits and equity to nonprofits advancing longevity research, including the Lifespan Research Institute (LRI), and support initiatives like the Dog Aging Project — helping dogs live longer, healthier lives while accelerating insights into human aging.
We believe the future of medicine begins before disease, and we’re building it now.
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These statements have not been evaluated by the Food and Drug Administration. This product/information is not intended to diagnose, treat, cure, or prevent any disease.
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