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The innovative drink that pioneered the science-based longevity movement — yours, in one simple blend.
The innovative drink that pioneered the science-based longevity movement — yours, in one simple blend.
Slow Aging
Increase Energy
Improve Skin Health
Support Balanced Mood
Improve Sleep
Enhance Cognition
Slow Aging
Increase Energy
Improve Skin Health
Support Balanced Mood
Improve Sleep
Enhance Cognition
“In a sea of generic supplement suppliers with just a packaging and marketing department, NOVOS’ commitment to research is a clear outlier.“
– Forbes
“Novos are pioneers in consumer longevity and among the first to develop a comprehensive approach that targets 12 mechanisms of aging simultaneously.”
— The Wall Street Journal
“Maybe it doesn’t take millions of dollars, over 100 daily supplements, and a team of 30 doctors to combat the aging process.”
— Business Insider
“Wealthy men are spending millions to lower their biological ages and live longer. These women are beating them with cheaper solutions [NOVOS]”
– Fortune
“In a groundbreaking study, NOVOS Core extended aged mouse lifespan by 18%—more than any supplement ever studied.“
— The Wall Street Journal
NOVOS Core is our all-in-one longevity mix, created to combat aging at the cellular level. Our most powerful formulation.
Key Highlights of NOVOS Core:
The primary longevity ingredients are:
Other natural ingredients: Erythritol*, Malic Acid, Natural Flavors, Sodium Bicarbonate, Silicon Dioxide, Calcium Silicate, Stevia**
* Erythritol only in Orange, not in Unflavored or Tropical Passion
** Stevia only in Orange and Tropical Passion, not in Unflavored
NOVOS Core is calorie free and sugar free. No artificial colors, preservatives or additives. Suitable for vegans. Non-GMO.
Designed by leading doctors and scientists specializing in aging, our formulation is rooted in the latest clinical research.
Our 100% vegan, sugar-free, and gluten-free formula meets the highest standards for your health and peace of mind.
Independently verified by third-party labs to guarantee the highest standards of purity and potency.
100% of our products are manufactured in the U.S.A., from the most pure, 3rd party tested ingredients sourced from trusted partners across the globe.
Designed by leading doctors and scientists specializing in aging, our formulation is rooted in the latest clinical research.
Our 100% vegan, sugar-free, and gluten-free formula meets the highest standards for your health and peace of mind.
Independently verified by third-party labs to guarantee the highest standards of purity and potency.
100% of our products are manufactured in the U.S.A., from the most pure, 3rd party tested ingredients sourced from trusted partners across the globe.
The evidence that makes NOVOS the most scientifically validated longevity ecosystem on the market. Learn more.
In a recent study of aged mice, NOVOS Core increased lifespan by 18%, surpassing all previously studied supplements in similar research, including NAD+ boosters like nicotinamide riboside.
In just 6 months, 73% of NOVOS Core and NOVOS Boost users experienced a significant reduction in their biological aging pace, with an average slowdown of 8.7% which works out to be 31.75 days younger per year. Nobody’s aging sped up.
Ingredients in NOVOS Core reduced the size of human senescent cells (cells that age and become toxic) by approximately 50% in an in-vitro study, offering effects comparable to a pharmaceutical longevity drug, rapamycin*.
After 6 months, all participants experienced increased skin firmness by an average of 22%, enhancing both appearance and feel.
NOVOS Core users ranked (#2, #5, and #7) for lowest rates of aging in a global competition that uses the DunedinPACE algorithm created by Duke and Columbia scientists to measure epigenetic changes.
Ingredients in NOVOS Core were able to prevent DNA damage by up to 77% in skin cells exposed to irradiation (e.g., UV rays) in an in-vitro study. In another human skin cell study, DNA was protected from moderate and high intensity chemo drugs.
NOVOS Core’s ingredients reduced unwanted cell death processes called oxytosis/ferroptosis, by 50%, while also reducing cellular inflammation, in an in-vitro human cellular study.
In a recent study of aged mice, NOVOS Core increased lifespan by 18%, surpassing all previously studied supplements in similar research, including NAD+ boosters like nicotinamide riboside.
In just 6 months, 73% of NOVOS Core and NOVOS Boost users experienced a significant reduction in their biological aging pace, with an average slowdown of 8.7% which works out to be 31.75 days younger per year. Nobody’s aging sped up.
Ingredients in NOVOS Core reduced the size of human senescent cells (cells that age and become toxic) by approximately 50% in an in-vitro study, offering effects comparable to a pharmaceutical longevity drug, rapamycin*.
After 6 months, all participants experienced increased skin firmness by an average of 22%, enhancing both appearance and feel.
NOVOS Core users ranked (#2, #5, and #7) for lowest rates of aging in a global competition that uses the DunedinPACE algorithm created by Duke and Columbia scientists to measure epigenetic changes.
Ingredients in NOVOS Core were able to prevent DNA damage by up to 77% in skin cells exposed to irradiation (e.g., UV rays) in an in-vitro study. In another human skin cell study, DNA was protected from moderate and high intensity chemo drugs.
NOVOS Core’s ingredients reduced unwanted cell death processes called oxytosis/ferroptosis, by 50%, while also reducing cellular inflammation, in an in-vitro human cellular study.
Mitochondria are crucial for energy production in cells; their dysfunction leads to decreased energy and cellular/organ aging. Malate and Calcium Alpha-Ketoglutarate enhance mitochondrial function and energy output.
Cells that cease to divide accumulate as senescent or “zombie” cells, contributing to aging and tissue degradation. Fisetin helps clear these cells, rejuvenating tissues and enhancing cellular function.
Proteostasis involves maintaining cell function by ensuring proteins fold and function properly. Loss of proteostasis leads to diseases and aging. Glycine and Hyaluronic Acid aid in maintaining protein integrity and function.
Effective communication between cells diminishes with age, leading to increased inflammation and cellular decline. L-Theanine and Glucosamine help maintain cellular communication, enhancing adaptability and resilience.
Increased accumulation of DNA damage contributes to aging and the development of age-related diseases. Pterostilbene and Magnesium help protect DNA, maintaining genomic stability.
Changes in epigenetic control of gene expression can lead to dysfunction and aging. Vitamin C and Calcium Alpha-Ketoglutarate have beneficial effects on epigenetic regulation, promoting healthier aging.
Telomeres protect the ends of chromosomes, and their shortening through repeated cell divisions leads to cell aging and death. Pterostilbene and Microdosed Lithium support the maintenance of telomere length, enhancing cellular longevity.
Aging affects the body’s ability to sense and respond to nutrients, impacting metabolism properly and growth pathways. Fisetin and Malate play a critical role in regulating these nutrient-sensing pathways.
With age, stem cells’ regenerative capacity diminishes, impairing the body’s ability to repair and regenerate tissues. Glycine and Calcium Alpha-Ketoglutarate support stem cell function and regenerative capacity.
Macroautophagy involves the degradation and recycling of cellular debris and dysfunctional components; its decline is linked to aging. Glucosamine and Fisetin promote the autophagic process, aiding cellular renewal and longevity.
Chronic, low-grade inflammation increases with age, contributing significantly to the progression of age-related diseases. Ginger and Pterostilbene mitigate inflammation, enhancing cellular health and longevity.
An imbalance in the gut microbiome can lead to a host of health issues and is linked to aging. Rhodiola rosea and Fisetin support a healthy gut microbiome, promoting overall well-being.

Feel a noticeable boost in daily energy levels and a more stable, balanced mood as cellular repair begins.

Experience improved skin hydration and elasticity as cellular rejuvenation enhances overall skin health.

Sharper focus, enhanced memory, and improved cognitive performance.

Measurable improvement in biological aging, supported by improved DNA repair, mitochondrial function, and more.
Change You Can See & Feel Within 2 Weeks
Scientifically
Studied
3rd-Party
Tested
Sugar &
Gluten-free
High-Quality
Ingredients
Vegan & All
Natural
NOVOS Core is rated 4.8 out of 5 stars. We have collected 1331 ratings.
The reason I first try the Novo’s Core was desperation to reduce my CRP (C-reactive Protein). I used anti inflammatory powder before from my local Herbal store, and it was good. My CRP number was 8.5 and after 28 days of using the powder from the local store it brings down to 1.0. I stopped couple of months and it went back up again to 8.1. after searching I’ve found Novo’s Core stating that it’s anti inflammatory drink. I ordered, start taking it. I did some blood work fifteen days later and it come down to .9. I’m trying to find out what causes my body’s inflammatory responses. I started Novo’s Core 2023 on and off now it looks different from the old one. Maybe it is just the packaging.
As a drink I blend with some fruits and it is delicious.
I’m 61 w/ chronic inflammation. Moving back to a colder climate moved me from less active to downright wanting to quit. I had to lean and hold on to railings, & the chronic pain in my hips, knees, hands & feet were making movement intolerable, so much so, I chose to sit more and more. In my quest for answers for anti-inflammatory care/cures, I stepped into the longevity world; something I balked at. After reading some testimonies on your product I decided to give them a try. I wish I had started them separately-but I took Core and Vital at the same time. On day 6, I got out of bed, and flew down the stairs…midway down I realized I didn’t need to hold on to the rail. And I ran up the stairs to be sure…The pain was 80% gone! * there may be permanent damage from the years of inflammation. It has been 9 days. I am almost pain free. I ate badly one day and thought I’d pay for it. I didn’t feel as good but wanted to see if this was just the improved food or the NOVOS. I am not going to “test” anymore. With NOVOS Core and Vital, I am not going to take this for granted. I am going to continue to improve my diet and exercise and see just how much healthier and stronger I can get! I am more focused, excited about life and my future. I am hoping more improvements will come. If they do, I’ll be sure to let you know. So grateful for the brave scientists who work with integrity to help humans live the rich life God intended for His kids. God bless you!
Fantastic product and fantastic customer service! I highly recommend the NOVOS line. I’ve been taking them for 6 months and can see (skin) and feel (energy levels, sense well being) the difference. Also, I prefer the Orange flavored Core vs the unflavored version.
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NOVOS Boost improves your metabolism, energy production, and DNA repair by raising NAD+ levels with NMN.
NOVOS Core contains 12 research-backed longevity ingredients:
The Orange flavor also includes erythritol, malic acid, stevia, and natural flavors. Core is vegan, non-GMO, sugar-free, and free from artificial colors and preservatives.
The focus is on the long-term. Remember that the key benefits of achieving maximum lifespan potential may not be perceived on a daily basis, as it impacts biology over time with consistent daily use on your Longevity Journey.
Many customers report seeing or feeling a noticeable benefit within 30 days. However, everyone’s body is different, and the benefits you may see or feel (skin health, energy, mood, etc.) are often just the most visceral ones.
Some people feel results in as a little as 7 days due to specific benefits like skin health and cognitive support.
Other longer term benefits like mitochondrial health and genomic stability may take longer, or you may not notice anything at all. That’s completely normal.
As long as you continue your daily intake, those beneficial nutrients are doing their work inside to optimize your health.
NOVOS Core is designed for adults of all ages who want to proactively support healthy aging.
NOVOS Core is free from:
It suits vegan, vegetarian, Mediterranean, keto, gluten-free, and NOVOS Longevity Diet guidelines.
Core is generally safe to take with other supplements, and many users replace overlapping ingredients like Vitamin C or magnesium.
There are no known contraindications with medications, but always consult your doctor before adding any new supplement to your routine.
A small percentage of users experience temporary stomach discomfort when starting Core. Taking it with food, splitting the dose, or mixing it with extra water typically resolves this within a few weeks.
NOVOS recommends avoiding Core during pregnancy and breastfeeding as a precaution.
No. Store Core at room temperature in a cool, dry place.
Yes. NOVOS Core ships to many countries worldwide. Shipping times vary but typically take 7–10 business days. Read more about our shipping policy.
While you can’t change your chronological age, biological age can vary based on lifestyle. NOVOS focuses on supporting the processes associated with healthy aging and helping slow the rate at which biological aging occurs.
It’s best to take Core with food. Taking any new supplement on an empty stomach may cause temporary digestive sensitivity in some people.
NOVOS Core is formulated to support multiple biological processes linked to healthy aging. Its ingredients are selected to help promote:
Short-term benefits reported by customers include improved energy, focus and skin appearance, while long-term benefits depend on consistent daily use.

