Ultra-Pure NMN Supplement

NOVOS Boost

The direct precursor to NAD+. At >99% purity.

4.91,119 ratings

Support your cellular energy and recovery with NOVOS Boost, an ultra-pure NMN supplement. Take two capsules daily for 250 mg of NMN to support your body’s natural NAD+ production. Each bottle holds 60 capsules, a one-month supply. Vegan, sugar-free and gluten-free.

  • Supports cellular energy and recovery*
  • Supports NAD+-dependent DNA repair and epigenome maintenance*
  • Supports metabolic health*
  • >99% pure NMN, third-party tested
  • Pairs with NOVOS Core for more comprehensive longevity support*
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Key ingredient

Two capsules deliver 250 mg of ultra-pure (>99%) nicotinamide mononucleotide in a next-generation, stable crystal form. The less than 1% of impurities are only nicotinamide, NR, and water. Third-party tested by Light Labs.

How to use

Take two capsules once or twice a day, with or without a meal. 250 mg to 500 mg a day is the range we recommend, on a regular basis. Or open the capsules and pour the pure contents under your tongue. No refrigeration needed.

Shipping & subscription

Free shipping. Pause, skip, or cancel anytime from your account, up to 1 business day before your renewal date. HSA and FSA eligible.

Clean formulation

Vegan, sugar-free, gluten-free. Each bottle holds 60 capsules, a one-month supply.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Verified customer reviewsIndividual results may vary.

“I feel a subtle but real energy when I take Boost.” Gianni M.. “I feel younger every day with Novos Boost.” Martha R.. “Better mood, more focused, loving it.” Carine Z.. “I have been taking Boost for over 1yr and noticed a rise in my energy after only a few months.” MA. Verified customer reviews. Individual results may vary.

NOVOS Boost benefit areas

Cellular energy and endurance

NAD+ helps cells convert nutrients into usable energy.

Learn more about Cellular energy and endurance

DNA repair and cellular maintenance

NAD+ supports enzymes involved in healthy DNA repair and epigenome maintenance.

Learn more about DNA repair and cellular maintenance

Metabolic health

NAD+ helps cells sense nutrients and maintain healthy metabolic function.

Learn more about Metabolic health

Support NAD+ levels that naturally decline with age.

NOVOS Boost provides ultra-pure NMN, the direct precursor your body uses to produce NAD+.

Daily NMN support.

NOVOS Boost supports NAD+ production with NMN, with changes in NAD+ metabolism measured in human studies.

Every day

Simple daily NAD+ support

Two small capsules provide 250 mg of ultra-pure NMN, without stimulants or caffeine.

Within weeks

Supports higher NAD+ levels

Human studies of NMN have shown increases in blood NAD+ and related NAD+ metabolites.

Over time

Supports energy and recovery

Healthy NAD+ production supports the cellular processes involved in energy metabolism and recovery.

With consistent use

Supports healthy aging biology

NAD+ supports enzymes involved in DNA repair, epigenome maintenance, and metabolic health.

With consistent use

Supports better sleep and daytime energy

In human studies, NMN improved sleep quality and reduced daytime drowsiness.

Results from clinical studies of NMN.

As we age, our NAD+ levels decline by as much as

87% in organs like skin, from birth to middle age.1

The results below come from independent clinical studies of NMN, the single ingredient in NOVOS Boost, at the daily doses shown. NOVOS Boost itself was not studied.

01

NAD+ levels · Randomized clinical study of NMN

2.6× higher

Blood NAD+ levels reached up to 2.6× baseline after 12 weeks of 250 mg daily NMN supplementation in older men.2

02

Metabolic health · Randomized clinical study of NMN

25% improvement

A measure of skeletal-muscle glucose metabolism improved after 10 weeks of 250 mg daily NMN in the studied population.3

  1. Age-associated changes in oxidative stress and NAD+ metabolism in human tissue, PLOS ONE, 2012
  2. Chronic nicotinamide mononucleotide supplementation elevates blood NAD+ levels and alters muscle function in healthy older men, npj Aging, 2022
  3. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women, Science, 2021

Results are from independent studies of NMN or NAD+ biology, not studies of NOVOS Boost. Study products, doses, durations, populations, designs, and outcomes varied. “Up to” figures reflect the largest reported mean change in the cited study and do not represent the percentage of participants who experienced a benefit. Results may not apply to generally healthy adults or predict individual outcomes.

Choose daily NMN
or the Core formula.

Pair NOVOS Boost with NOVOS Core for more comprehensive longevity support.

Feature This productNOVOS Boost The foundationNOVOS Core
What it is 250 mg ultra-pure NMN 12-ingredient daily longevity formula
What it supports NAD+, cellular energy, DNA maintenance, metabolic health Ingredients selected using research on the Hallmarks of Aging
Research Published human studies on NMN Finished formula studied in randomized, placebo-controlled human clinical trial
Add NOVOS Core to your routine

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Real scientists. Real doctors.

NOVOS is built with guidance from scientists and physicians from Harvard Medical School and MIT, whose expertise spans aging biology, genomics, neurobiology, nutrition, and clinical medicine.

Scientific advisors: Dr. Pamela Maher (Salk Institute), Dr. J. Pedro Magalhães (Harvard Medical School), Dr. George Church (Harvard Medical School and MIT), Dr. Robert Lufkin (USC School of Medicine), Dr. Diogo Barardo (National University of Singapore), Dr. Oliver Medvedik (Cooper Union), and Dr. Avi Rosenbaum (scientist and biotech consultant).

8 yrsof research
7scientists & MDs formulated
8whole formulation studies
450+ingredient studies
2,000+clinicians shared NOVOS on FrontrowMD
3rdparty-tested for purity & potency
“NOVOS takes a disciplined, biology-first approach in a space that too often prioritizes hype over evidence.”
Dr. Doina Kulick, M.D.Lead Physician, Longevity Medicine · Mayo Clinic Arizona

Available at

NOVOS available at Mayo Clinic Store, Bumrungrad International Hospital, Erewhon, Equinox, Remedy Place, Four Seasons, and Sunlife Organics.

Customer reviews.

4.9

Based on 1,119 ratings

· Joshua N.

Customers Care

Whenever you inquire about product information or purchasing, always assist you and reply in time, very helpful and impressive customer care team.

· Olivier B.

Great stuff

Great stuff

· Community Member

Scientific Authority

I very much appreciate the extensive, authoritative, and well documented advice and explanations. I have linked your large website to many of my friends and family.

· Michele G.

Love it right from the start..

The Novos core and the boost arrived in 3 days after I placed my order…I live in Hawaii and waiting 2 weeks or more for things to be delivered is normal here but Novos was different and they were fast..I used to take all the different supplements and it took me awhile swallowing them and was not pleasant, but with the Novos it goes down easily with one drink. I chose the non-flavor Novos Core and it actually has a pleasant light orangey taste..I am loving it so far..

· Jody H.

So far so good!

I have only been on Novos core and boost for about a month but can see changes in my energy level. I am excited to see more changes. I have had compliments on my skin as well.

· Alexander F.

It’s working !

Great products ! I’ve been using your Novos core + boost products for three months already and I feel much better than before – more energy , better mobility , better memory . It’s definitely working for me !

Individual experiences may vary and are distinct from results observed in controlled clinical research.

Everything you might want to know.

Conversion-ordered. Short answers, longer answers a tap away.

When will I feel results?
Some people notice changes in energy or recovery immediately, while other benefits may be subtle and build with consistent use over weeks to months. Human NMN studies have generally evaluated outcomes over several weeks to several months. Individual results vary.
What is NMN, and how does it support NAD+?
NMN, or nicotinamide mononucleotide, is a direct precursor your body uses to produce NAD+. NAD+ supports cellular energy production, DNA maintenance, metabolic health, and other essential cellular processes. NAD+ is not orally bioavailable for direct administration.
Is NOVOS Boost clinically studied?
NOVOS Boost itself has not been clinically studied. However, it is made with just one ingredient—NMN—an ingredient evaluated in multiple human clinical studies, including randomized, placebo-controlled trials.
How is NMN different from NR and other NAD+ precursors?
NMN is the direct precursor to NAD+. Earlier-stage precursors such as NR require an additional conversion step before becoming NMN and then NAD+. Both NMN and NR have been studied in humans, but NOVOS chose ultra-pure NMN for its direct role in NAD+ production.
How much NOVOS Boost should I take?
Take two capsules for 250 mg of NMN. This serving may be taken once or twice daily. Follow the product directions and speak with your healthcare professional before taking higher amounts.
When and how should I take it?
NOVOS Boost can be taken with or without food. Swallow the capsules with water, or open them and take the filler-free powder directly (e.g., under your tongue) or mix it into water. Consistency matters more than the precise time of day.
Why does NOVOS Boost use two capsules?
Two small capsules deliver a complete 250 mg serving while keeping the capsules easy to swallow. The formula contains NMN without added fillers or unnecessary excipients.
Why pair NOVOS Boost with NOVOS Core?
Boost provides focused NAD+ support through NMN. Core is a broader, 12-ingredient longevity formula whose ingredient selection was guided by research on the Hallmarks of Aging. They can be used together as complementary parts of a more comprehensive longevity routine.
Is NOVOS Boost safe with my medications or other supplements?
NMN has been well tolerated in published human studies, but individual circumstances differ. Consult your healthcare professional before use if you take medication, manage a medical condition, are preparing for surgery, or use other supplements that affect similar pathways.
Who should not take NOVOS Boost?
Do not use it if you are pregnant, nursing, under 18, or have been advised by a healthcare professional to avoid NMN. People with medical conditions or those taking medication should consult their healthcare professional before use.
How is NOVOS Boost tested?
NOVOS Boost is third-party tested for identity, purity, potency, and contaminants. Lot-level testing results are published so customers can review the quality of the product they receive.
How should I store NOVOS Boost?
No refrigeration is needed. Store it tightly closed in a cool, dry place away from heat, moisture, and direct light.
Can I cancel or pause my subscription?
Yes. You can pause, skip a delivery, or cancel anytime from your account. No phone calls, no lock-in.
Is NOVOS Boost HSA/FSA eligible?
Yes. NOVOS Boost may qualify for HSA/FSA reimbursement through our partner Truemed. Look for the Truemed option at checkout.
Where is it made?
NOVOS Boost is manufactured in the U.S.A. in cGMP facilities, using rigorously tested ingredients from trusted partners worldwide.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.

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Click-through evidence · Cellular energy and endurance

Cellular energy and endurance

NAD+ is the molecule your cells use to turn food into usable energy. Levels fall as we age. NOVOS Boost is made with ultra-pure NMN, which your body uses to support its own NAD+ production.

  • Human NMN research
  • 250 mg per serving
  • No caffeine, no stimulants

In a randomized, placebo-controlled human study, 250 mg of NMN a day for 12 weeks significantly increased blood NAD+ levels in healthy older men.

Published research on the NMN ingredient, not on NOVOS Boost. The study used 250 mg of NMN a day, the amount in one 2-capsule serving of NOVOS Boost. Study population results are not a guarantee of individual outcomes. Individual results may vary.

Source: Igarashi et al., npj Aging, 2022

Click-through evidence · DNA repair and cellular maintenance

DNA repair and cellular maintenance

NMN is a building block of NAD+, an important molecule that enzymes need in order to support healthy DNA, maintain the epigenome, and ensure cellular integrity.

  • Human NMN research
  • Telomere markers
  • 300 mg/day, 90 days

In a published human study of men aged 40 to 60, researchers reported significant changes in telomere-length markers in peripheral blood mononuclear cells at the 300 mg/day NMN dose over a 90-day observation period.

Published research on the NMN ingredient, not on NOVOS Boost. Single study, small sample size; replication pending. Individual results may vary.

Source: Niu et al., Frontiers in Nutrition, 2021

Click-through evidence · Metabolic health

Metabolic health

NAD+ sits at the center of how cells sense and use nutrients. That machinery changes with age.

  • Human NMN research
  • 250 mg/day, 10 weeks
  • Postmenopausal women

In a randomized, placebo-controlled trial, postmenopausal women with prediabetes who were overweight or obese took 250 mg of NMN a day for 10 weeks. Their muscle insulin sensitivity was 25% higher than before, and muscle insulin signaling increased.

Published research on the NMN ingredient, not on NOVOS Boost. Study population results are not a guarantee of individual outcomes. Individual results may vary.

Source: Yoshino et al., Science, 2021

Key ingredient

Two capsules deliver 250 mg of ultra-pure (>99%) nicotinamide mononucleotide in a next-generation, stable crystal form. Third-party tested by Light Labs.

NOVOS Boost Supplement Facts label: 250 mg of NMN per two-capsule serving.

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