What's NOVOS Core made of? What's NOVOS Boost made of?

See the NOVOS Core Orange nutrition label and Unflavored nutritional label. The primary longevity ingredients are: Vitamin C Magnesium Malate Calcium Alpha-Ketoglutarate Glycine Glucosamine Sulfate Rhodiola Rosea L-Theanine Hyaluronic Acid Fisetin Gingerol Pterostilbene Micro-dosed Lithium Other natural ingredients: Erythritol*, Malic Acid, Natural Flavors, Sodium Bicarbonate, Silicon Dioxide, Calcium Silicate*, Stevia* *ingredients only in Orange, not in Unflavored NOVOS Core is calorie free and sugar free. No artificial colors, preservatives or additives. Suitable for vegans. Non-GMO. See the NOVOS Boost nutrition label. NOVOS Boost is made of 1 key longevity ingredient: β-Nicotinamide Mononucleotide (NMN). Other ingredients: Vegetable cellulose. No artificial colors, preservatives or additives. Gluten-free. Non-GMO. Suitable for vegans. GMP certified.

When will I see or feel results?

The focus is on the long-term. Remember that the key benefits of achieving maximum lifespan potential may not be perceived on a daily basis, as it impacts biology over time with consistent daily use on your Longevity Journey. Many customers report seeing or feeling a noticeable benefit within 30 days. However, everyone’s body is different, and the benefits you may see or feel (skin health, energy, mood, etc.) are often just the most visceral ones. Some people feel results in as a little as 7 days due to specific benefits like skin health and cognitive support. Other longer term benefits like mitochondrial health and genomic stability may take longer, or you may not notice anything at all. That’s completely normal. As long as you continue your daily intake, those beneficial nutrients are doing their work inside to optimize your health.

Who is NOVOS Core for?

NOVOS Core is meant for early-adult, middle-aged and elderly people. It is developed to slow down aging, a process that already starts from a young age. The most pronounced short-term effects will be noticed by older people, while the greatest long-term longevity benefits will come from starting at a younger age. NOVOS Boost should be thought of as an add-on to our foundational product, NOVOS Core.

Is NOVOS Core compatible with my diet or dietary restrictions?

NOVOS Core and NOVOS Boost are free from: Dairy Gluten Soy GMOs Nuts Sugar Calories Shellfish Sesame Glyphosate/AMPA Binders Preservatives 14 classes of allergens defined by European Food and Safety Authority (EFSA). Both adhere to the following diets: Vegan Vegetarian Ketogenic Gluten Free Mediterranean NOVOS Longevity Diet

Can I take NOVOS Core and/or NOVOS Boost with other supplements and medications?

NOVOS Core and NOVOS Boost are both safe to take with other supplements. There are no known contraindications with NOVOS Core or NOVOS Boost and any over-the-counter or prescription medications, though we encourage you to double check with your physician before adding our product to your regimen. If you are already taking any ingredients found in the NOVOS Core formulation, such as magnesium or Vitamin C, you can consider discontinuing those supplements and simplifying your routine with NOVOS Core.

Are there any health risks associated with NOVOS Core?

A small percentage of users (less than 3%) report that they feel stomach discomfort when they first start taking NOVOS. This is normal: when a new food is introduced into your routine, it can take time for your microbiome and digestive tract to adapt. If this is the case for you, we recommend the following: Make sure you only take NOVOS Core on a full stomach. Split up your NOVOS Core into 2 to 3 servings. Pour 1/3 to 1/2 of the powder into your drink with each meal. Dilute NOVOS Core in a larger serving of water (16-24 ounces, rather than 8 ounces). Try steps 1-3 for a few weeks. In 90% of cases, the issue resolves itself. If it does not for you, feel free to contact our customer care team. While there are no known health risks with NOVOS Boost, we recommend starting with a minimum dose of 2 capsules per day and monitoring how you feel.

Are NOVOS Core and NOVOS Boost safe to take while I'm pregnant or breastfeeding?

To our knowledge, we don't see a problem with taking NOVOS during pregnancy. However, given that this is a very critical period in the development of your child, and given that there could be unknown unknowns, we recommend that you err on the side of caution. That is, we advise against taking NOVOS while pregnant (and while breastfeeding).

Do I need to refrigerate NOVOS Core?

For NOVOS Core, no refrigeration is needed. Storing at room temperature in a cool, dry environment is perfect for NOVOS Core. The main ingredient in NOVOS Boost is NMN. Ideally, you should store NMN in a cool, dry place – room temperature is perfectly fine. You can also store it in the refrigerator. Keep it out of light and avoid too high temperatures for extended periods of time.

What does my subscription to NOVOS Core+Boost include?

For monthly subscriptions, your order will contain 1 box of NOVOS Core and 1 bottle of NOVOS Boost. For prepaid options (6 or 12 months), you will receive all 6 or 12 boxes and bottles upfront.

What is your return policy?

If you have active subscriptions to any NOVOS products, you can change the renewal date, cancel or renew your subscriptions at any time, as often as you would like. If you wish to choose a different renewal date or cancel a subscription, it must be done at least 2 business days prior to the renewal date, otherwise the transaction will be considered complete. Keep in mind that every person’s body is different, and the short-term benefits you see or feel (skin health, energy, sleep, mood, etc.) should be considered as added benefits. As long as you continue your daily intake, the beneficial nutrients are doing their work inside to optimize your health. Consistent use is the key to slowing down your aging to be YoungerForLonger™. US-based purchases: If you still wish to return your NOVOS products (Core and/or Boost), it must be within thirty (30) days and each product must be unopened (still sealed). We never charge consumers shipping fees as we pay for the costs, and we will provide a prepaid return shipping label, so there will be a deduction of $25 per transaction to cover the back and forth shipping costs. There will also be a restocking fee of $35 per transaction (deductions will not exceed the value of the order). If you would like a NOVOS credit instead of a refund to your original payment method, we will waive the shipping and restocking fees ($60). NOVOS credit must be used within 1 year of issuance. All purchases of NOVOS Age are final. Non-US-based purchases: All international orders are final for all products. NOVOS is not responsible for any lost packages that were incorrectly addressed due to customer error. We generate shipping labels from the information the customer provides, so if you enter an incorrect or incomplete address (e.g., incorrect zip code, missing apartment/office number) and your package is lost, NOVOS is not responsible. We appreciate your understanding. If you input the incorrect address on your order and it has only just begun processing, try to cancel the order immediately by logging into your account. If you are unsure if this processed correctly, immediately email us at care@novoslabs.com with the new address information. Then, place your order again using the correct address. However, once your package is processed and shipped, we cannot make any more modifications to your shipment. We guarantee that our products will ship to you in excellent condition without any defects and we will replace the product free of charge within 30 days of purchase if the boxes or bottles come damaged. All NOVOS products undergo thorough quality assurance to ensure they meet our high standards. However, if you find a damaged or defective product upon arrival due to mishandling during shipping, you must submit a claim within 2 days of receiving your order. To create a claim, please email us at care@novsolabs.com and include: Your order/invoice number Contact information Description of defective products Images of packaging, shipping box, and invoice **Please keep all products and packaging as we may ask you to ship all defective products to us for additional inspection. If you do not complete this step, your claim may be denied. This return policy applies only to purchases made through www.novoslabs.com. If you purchased NOVOS products through a third-party marketplace and want to make a return, please contact that third-party marketplace.

Do you ship internationally?

Yes, we ship NOVOS Core and NOVOS Boost to many countries. Currently, NOVOS Age is only available in the United States. We ship Core and Boost to: Australia (not all zip codes), Austria, Brazil, Canada, Croatia, Denmark Finland, France, Germany, Greece, Hungary, Ireland, Israel, Japan Luxembourg, Malta, Monaco, Netherlands, New Zealand, Norway Poland, Portugal, Puerto Rico, San Marino, Singapore, Slovenia Spain, South Korea, Sweden, Switzerland, United Arab Emirates (UAE) United Kingdom (UK), United States (US), Virgin Islands (British), Virgin Islands (US) International shipping usually takes 7-10 business days, but can be faster or slower depending on many variables including location, custom delays, time of year, and more. Subscribe to our newsletter and follow on social (@novoslabs) to be the first to know when we expand international shipping.

Is it really possible to slow or reverse aging?

Yes. While you can't change the number of birthdays that have passed (chronological age), it is possible to slow down or accelerate your biological age based upon lifestyle changes.

NOVOS Longevity Stack - Longevity Drink + NMN Supplement

Verified customer reviews

“It’s definitely doing something.”Virginia G. “More energy and less fatigue.”Harriet B. “My skin looks firmer and healthier.”Chris H. “My bio age reduced to 48.6.”Jeffrey B. “Waited so long for a product like yours.”Charlotte F. “It’s definitely doing something.”Virginia G. “More energy and less fatigue.”Harriet B. “My skin looks firmer and healthier.”Chris H. “My bio age reduced to 48.6.”Jeffrey B. “Waited so long for a product like yours.”Charlotte F.

All 12 Hallmarks of Aging. Plus focused NAD+ support.

Pair NOVOS Boost with NOVOS Core for more comprehensive longevity support.

All 12 Hallmarks of Aging

An all-in-one longevity formula with 12 ingredients, designed to target all 12 Hallmarks of Aging. One sachet daily.

Focused NAD+ support

High-purity (>99%) NMN. Supports NAD+, which the body uses for cellular energy and DNA repair. Two capsules daily.

The full daily foundation

The daily foundation of the NOVOS protocol: broad coverage of aging biology, plus focused NAD+ support.

Feel the difference, inside and out.

Healthy aging

Designed to target all 12 root causes of aging at once.

Learn more

Cardiovascular health

Rapid, durable support shown in a placebo-controlled human trial.

Learn more

Cellular energy and endurance

NMN supports NAD+, the molecule cells use for energy. No caffeine.

Learn more

DNA repair and metabolic health

NAD+ supports healthy DNA and how cells sense and use nutrients.

Learn more

Improved skin

All pilot-study participants improved skin firmness.

Learn more

Improved sleep

Formulated with ingredients associated with restful sleep.

Learn more

81% of NOVOS customers feel a difference within 2 weeks.

The full daily foundation helps you keep doing what you love, for longer.

*Based on a customer survey 2 weeks post-purchase.

More good years. Starting now.

NOVOS Core works on the biology of aging, with effects clinically shown to build from the first dose.

+3.9%

From the first dose

Cardiovascular function responds right away

In a randomized, double-blind, placebo-controlled trial in healthy adults aged 40+, conducted at the University of Surrey, NOVOS Core showed benefits to cardiovascular function shortly after the very first dose.

Cardiovascular markers Learn more

Within days

A calmer, more rested feeling

NOVOS Core includes Glycine, an amino acid studied in connection with falling asleep more easily and feeling more refreshed in the morning, and L-Theanine, studied in connection with calm, steady focus. NOVOS Boost adds 250 mg of ultra-pure NMN in two small capsules, without stimulants or caffeine.

Sleep · NAD+ Support Learn more

Within weeks

Supports higher NAD+ levels

Human studies of NMN have shown increases in blood NAD+ and related NAD+ metabolites.

NAD+ metabolism Learn more

81%

The first few weeks

81% feel a difference within 2 weeks

Many customers report steadier energy and a calmer, more rested feeling within the first few weeks. NOVOS Core includes Rhodiola rosea, an adaptogen studied for its potential to support stamina, and ingredients associated with calm, restful sleep.

Energy · Sleep Learn more

~45%

The first few months

~45% mention energy, skin, and focus

Skin, focus, and an overall sense of well-being are the changes customers mention building over the first months.

Skin · Focus Learn more

+2.9% FMD

By six months

Sustained, measured change vs placebo

In a randomized, double-blind, placebo-controlled trial in healthy adults aged 40+, NOVOS Core showed sustained benefits to cardiovascular aging markers at six months: healthy arterial flexibility and healthy blood pressure (for blood pressures already in the normal range). In a separate pilot, all participants improved skin firmness, averaging 22%.

Cardiovascular · Skin firmness Learn more

73%

Measure the difference

73% slowed their pace of aging

In a case study, most participants took NOVOS Core and NOVOS Boost daily for six months, and most slowed their biological pace of aging, measured on the DunedinPACE algorithm. Some aged at roughly 11 months per calendar year instead of 12. With NOVOS Age, you can measure your own biological age before and after.

Pace of aging Learn more

What sets the bundle apart.

How NOVOS Core + Boost compares across the benefits that matter most.

Ingredient-level onlyVaries

Most “Longevity Supplements” Are Not Actually Longevity Supplements

And are never tested as the product you actually take.

In a randomized, double-blind, placebo-controlled human trial, the complete NOVOS Core formulation provided nutritional support for biological systems predictive of lifespan and healthspan.*

That’s the difference between claiming longevity and demonstrating measurable results.

“This trial provides rare human evidence that a multi-pathway nutritional strategy can meaningfully influence cardiovascular aging biology itself.”

Dr. Christian HeissProfessor of Cardiovascular Medicine, University of Surrey

FMD

Blood Flow

Flow-mediated dilation

How well your arteries open when your body needs more blood. In the trial, FMD improved +2.9% vs placebo — a leading marker of endothelial and vascular health.

PWV

Blood Vessel Flexibility

Pulse wave velocity

How flexible your arteries are. PWV typically worsens about 1 m/s per decade; the trial showed a 1.2 m/s improvement vs placebo.

SBP

Blood Pressure

Systolic blood pressure

The pressure on your artery walls with every heartbeat. In the trial, systolic BP fell 6.1 mmHg vs placebo for blood pressure already in the normal range.

Member of / Selected for

Randomized, double-blind, placebo-controlled human clinical research in healthy adults 40+. Manuscript under peer review. Read the clinical trial

Not just made for longevity. Studied for it.

NOVOS Core has been tested across the full arc of longevity research: DNA, cells, animal lifespan, epigenetic biological age, and placebo-controlled human research.

Read the clinical trial

01

Cardiovascular · Randomized Human Trial

Rapid, durable cardiovascular benefits.

In a randomized, double-blind, placebo-controlled trial in healthy adults aged 40+, NOVOS Core produced statistically significant improvements at six months in endothelial function, arterial flexibility, and systolic blood pressure (among participants already within the normal range).

Manuscript under peer review. Learn more

02

Cells & DNA · In Vitro

Up to 77% more DNA protection.

NOVOS Core ingredients supported DNA integrity by up to 77% in irradiated skin cells. The NOVOS combination outperformed its individual ingredients.

In vitro study. Not indicative of human outcomes. Learn more

03

Lifespan · Animal

18% longer lifespan.

In aged mice, NOVOS Core extended lifespan by over 18%, the highest yet recorded for an over-the-counter supplement in aged-mouse models.

Animal study. Results may not translate to humans. Animal studies are not relied upon to support any representations of health benefit in humans. Learn more

04

Biological Age · Case Study

73% showed a slower pace of aging score.

In a 12-participant case study (ages 39–76), 73% reduced their DunedinPACE score. No participant’s score increased.

Case study, n=12; not a controlled trial. DunedinPACE is a research-use algorithm correlated with biological pace of aging, not a direct or definitive measure of aging. Individual results may vary. Learn more

05

Skin Firmness · Pilot

22% firmer skin.

In a 6-month pilot (n=4), every participant improved skin firmness, averaging 22% (range 12% to 40%).

Pilot study, n=4. Preliminary. Individual results may vary. Learn more

Twelve ingredients in one daily formula.
One ingredient in one capsule.

No proprietary blends. Every dose disclosed.

NOVOS Core powder with a measuring spoon

No proprietary blends Vegan · gluten-free · sugar-free · erythritol-free Naturally sweetened with stevia (unflavored does not contain stevia)

Active ingredients

NOVOS Core

Twelve ingredients, one daily drink mix.

Calcium Alpha-Ketoglutarate
Fisetin
Pterostilbene
Glucosamine Sulfate
Glycine
Magnesium Malate
L-Theanine
Rhodiola Rosea
Gingerols and Shogaols
Hyaluronic Acid
Vitamin C
Micro-dosed Lithium

NOVOS Boost

>99% pure NMN (nicotinamide mononucleotide), 250 mg per two-capsule serving. No fillers.

No proprietary blends. Every dose printed on the label. Patent-pending.

13 longevity ingredients across two daily formulas. See every ingredient and dose

Real scientists. Real doctors.

NOVOS is built with guidance from scientists and physicians from Harvard Medical School and MIT, whose expertise spans aging biology, genomics, neurobiology, nutrition, and clinical medicine.

Dr. Pamela MaherSalk Institute

Dr. J. Pedro MagalhãesHarvard Medical School

Dr. George ChurchHarvard Medical School · MIT

Dr. Robert LufkinUSC School of Medicine

Dr. Diogo BarardoUniversity of Singapore

Dr. Oliver MedvedikBiomedical Engineering · Cooper Union

Dr. Avi RosenbaumScientist and biotech consultant

Dr. Pamela MaherSalk Institute

Dr. J. Pedro MagalhãesHarvard Medical School

Dr. George ChurchHarvard Medical School · MIT

Dr. Robert LufkinUSC School of Medicine

Dr. Diogo BarardoUniversity of Singapore

Dr. Oliver MedvedikBiomedical Engineering · Cooper Union

Dr. Avi RosenbaumScientist and biotech consultant

8 yrsof research

7scientists & MDs formulated

7whole formulation studies

950+ingredient studies

1,800+verified clinicians recommend

3rdparty-tested for purity & potency

NOVOS Available At

Mayo Clinic Store
Bumrungrad International Hospital
Erewhon
Equinox
Remedy Place
Four Seasons
Sunlife Organics

“NOVOS takes a disciplined, biology-first approach in a space that too often prioritizes hype over evidence.”

Dr. Doina Kulick, M.D.Lead Physician, Longevity Medicine · Mayo Clinic Arizona

Recommended by 1,800+ verified clinicians. Practitioner Program

Verified customer reviews.

5.0

Based on 89 ratings

· Rebecca Williams

Wish I could add products to my current subscription

It would be great if I could add products to my current subscription instead of adding a second subscription. Do I have to cancel my current subscription and make a new one to do so? It is a great product and you couldn't do better anywhere else. The science has really backed this one,

· Rick

Fantastic product and fantastic…

Fantastic product and fantastic customer service! I highly recommend the NOVOS line. I've been taking them for 6 months and can see (skin) and feel (energy levels, sense well being) the difference. Also, I prefer the Orange flavored Core vs the unflavored version.

· Moncie

Helping with bad case of long Covid

I experienced a very bad case of Covid in 2022 and have had long Covid symptoms since then. I’ve been on it for little over a month, maybe a month and a half at this point, and I FINALLY feel like I’m getting back to my old self physically. My fatigue has decreased significantly and I don’t feel as wiped out as I used to. I’m able to do my everyday tasks with much more energy than before and things have gotten much easier. I’m so grateful to have found this and would recommend it to anyone. I’ve already cancelled my monthly subscription and purchased the annual. I used to waste so much money on supplements that didn’t work and think Novos is totally worth it, even if it is on the pricey side. If you’re having health issues can’t hurt to try this!

· Lisa H.

One month in

I’m coming up on my first month of core + boost—and it’s really already changing my energy levels. I just feel BETTER. I can’t wait to see the benefits at the 3,6, and 12 month mark!!

· Manuel M.

Antidotally, it helps

Antidotally, I think it helps my ability to think and organize.

· Sean H.

It's great!

I’ve been using NOVOS for almost 3 years now and I think it’s great. I only wish they could add Urolithin A to it so I don’t have to buy another expensive supplement as well.

Individual experiences may vary and are distinct from results observed in controlled clinical research.

Questions, answered.

Everything you need to know about NOVOS, the science, and getting started.

Why take NOVOS Core and NOVOS Boost together?

NOVOS Core is a 12-ingredient longevity formula designed around all 12 Hallmarks of Aging. NOVOS Boost provides focused NAD+ support through 250 mg of >99% pure NMN. They can be used together as complementary parts of a more comprehensive longevity routine.

When will I feel results?

Many customers notice subtle changes in clarity and energy in the first few days. Broader changes (energy, sleep, skin) typically build over weeks to months. Human NMN studies have generally evaluated outcomes over several weeks to several months. Biological-age changes develop over a longer horizon and depend on baseline health and consistent use. Individual results may vary.

What’s in NOVOS Core?

Twelve science-backed longevity ingredients in one daily drink mix. No proprietary blends, every dose disclosed. See the full ingredient and dose list.

What is NMN, and how does it support NAD+?

NMN, or nicotinamide mononucleotide, is a direct precursor your body uses to produce NAD+. NAD+ supports cellular energy production, DNA maintenance, metabolic health, and other essential cellular processes. NAD+ is not orally bioavailable for direct administration.

Is NOVOS Boost clinically studied?

NOVOS Boost itself has not been clinically studied. However, it is made with just one ingredient, NMN, an ingredient evaluated in multiple human clinical studies, including randomized, placebo-controlled trials.

How much should I take of each?

One sachet of NOVOS Core daily, mixed into water. Two capsules of NOVOS Boost for 250 mg of NMN, once or twice daily. Follow the product directions and speak with your healthcare professional before taking higher amounts.

When and how should I take them?

Most customers take both in the morning. NOVOS Boost can be taken with or without food. Consistency matters more than the precise time of day.

Is it safe with my other supplements or medications?

Both products are formulated for tolerability and long-term daily use. If you take prescription medications, manage a medical condition, are preparing for surgery, or have a medical condition, share the ingredient list with your healthcare provider before starting.

How does NOVOS Core compare to IM8 / AG1 / Mitopure / Blueprint?

Greens powders cover general nutrition and single-pathway products target one mechanism. NOVOS Core addresses the root causes of aging across multiple pathways, and is backed by a randomized, placebo-controlled human clinical trial on the finished formula.

How is NMN different from NR and other NAD+ precursors?

NMN is the direct precursor to NAD+. Earlier-stage precursors such as NR require an additional conversion step before becoming NMN and then NAD+. Both NMN and NR have been studied in humans, but NOVOS chose ultra-pure NMN for its direct role in NAD+ production.

What does NOVOS Core taste like? (Orange vs Unflavored)

Orange is a light citrus flavor with no artificial sweeteners. Unflavored is neutral and disappears into water, smoothies, or your favorite drink.

What if I’m sensitive to supplements?

Start with half a pack of NOVOS Core for the first week and build up. The formula is vegan, sugar-free, gluten-free, and free of artificial sweeteners. If sensitivities persist, consult your healthcare provider.

Can I cancel or pause my subscription?

Yes. You can pause, skip a delivery, or cancel anytime from your account. No phone calls, no lock-in.

Is there a money-back guarantee?

Yes. If the bundle isn’t right for you, contact our support team about your first order and we’ll make it right.

Is the bundle HSA/FSA eligible?

Yes. NOVOS Core and NOVOS Boost may qualify for HSA/FSA reimbursement through our partner Truemed. Look for the Truemed option at checkout.

Who are these products not for?

Both are designed for healthy adults. They are not intended for anyone under 18, or for those who are pregnant or nursing. If you have a medical condition or take medications, talk with your healthcare provider first.

How are they tested?

Both are third-party tested for identity, purity, potency, and contaminants. Lot-level testing results are published so customers can review the quality of the product they receive.

Where are they made?

Both are manufactured in the U.S.A. in cGMP facilities, using rigorously tested ingredients from trusted partners worldwide.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.

NOVOS Core+Boost

Two formulas, one longevity protocol

All 12 Hallmarks of Aging. Plus focused NAD+ support.

All 12 Hallmarks of Aging

Focused NAD+ support

The full daily foundation

NOVOS Core + Boost benefit areas

Healthy aging

Cardiovascular health

Cellular energy and endurance

DNA repair and metabolic health

Improved skin

Improved sleep

More good years. Starting now.

Cardiovascular function responds right away

A calmer, more rested feeling

Supports higher NAD+ levels

81% feel a difference within 2 weeks

~45% mention energy, skin, and focus

Sustained, measured change vs placebo

73% slowed their pace of aging

What sets the bundle apart.

Most “Longevity Supplements” Are Not Actually Longevity Supplements

Blood Flow

Blood Vessel Flexibility

Blood Pressure

Not just made for longevity. Studied for it.

Rapid, durable cardiovascular benefits.

Up to 77% more DNA protection.

18% longer lifespan.

73% showed a slower pace of aging score.

22% firmer skin.

Twelve ingredients in one daily formula.One ingredient in one capsule.

NOVOS Core

Real scientists. Real doctors.

Independent Clinician Evaluations

Verified customer reviews.

Wish I could add products to my current subscription

Fantastic product and fantastic…

Helping with bad case of long Covid

One month in

Antidotally, it helps

It's great!

Questions, answered.

Twelve ingredients in one daily formula.
One ingredient in one capsule.