Clinically Studied NMN

NOVOS Boost

The direct precursor to NAD+. At >99% purity.

Ultra-pure NMN for NAD+ support. 250 mg per serving, in two tiny capsules.

4.91,119 ratings

NAD+ Support Formula. Formulated with NMN to support cellular energy production, metabolic health, and DNA maintenance.

  • Supports cellular energy and recovery*
  • Supports NAD+-dependent DNA repair and epigenome maintenance*
  • Supports metabolic health*
  • >99% pure NMN, third-party tested
  • Pairs with NOVOS Core for more comprehensive longevity support*
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Verified customer reviewsIndividual results may vary.

“I feel a subtle but real energy when I take Boost.” Gianni M.. “I feel younger every day with Novos Boost.” Martha R.. “Works better than other brands I’ve used.” Mary K P.. “Better mood, more focused, loving it.” Carine Z.. “I have been taking Boost for over 1yr and noticed a rise in my energy after only a few months.” MA. Verified customer reviews. Individual results may vary.

NOVOS Boost benefit areas

Cellular energy and endurance

NAD+ helps cells convert nutrients into usable energy.

Learn more about Cellular energy and endurance

DNA repair and cellular maintenance

NAD+ supports enzymes involved in healthy DNA repair and epigenome maintenance.

Learn more about DNA repair and cellular maintenance

Metabolic health

NAD+ helps cells sense nutrients and maintain healthy metabolic function.

Learn more about Metabolic health

Support NAD+ levels that naturally decline with age. NOVOS Boost provides clinically studied NMN, the direct precursor your body uses to produce NAD+.

More cellular energy. Starting within weeks.

NOVOS Boost supports NAD+ production with clinically studied NMN, with changes in NAD+ metabolism measured in human studies.

Within days

Simple daily NAD+ support

Two small capsules provide 250 mg of ultra-pure NMN, without stimulants or caffeine.

Within weeks

Supports higher NAD+ levels

Human studies of NMN have shown increases in blood NAD+ and related NAD+ metabolites.

Over time

Supports energy and recovery

Healthy NAD+ production supports the cellular processes involved in energy metabolism and recovery.

With consistent use

Supports healthy aging biology

NAD+ supports enzymes involved in DNA repair, epigenome maintenance, and metabolic health.

With consistent use

Supports better sleep and daytime energy

In human studies, NMN improved sleep quality and reduced daytime drowsiness.

Why NOVOS chose NMN.

How NOVOS Boost compares with typical NAD+ supplements.

Feature NMNNOVOS Boost Typical NAD+ Supplements
NOVOS Boost uses NMN (nicotinamide mononucleotide). NR-based products use nicotinamide riboside, a different precursor. Both raise NAD+. NMN is the precursor with the stronger consumer mindshare, and the FDA confirmed its lawful status as a dietary supplement in September 2025. Direct Requires extra steps
Human studies Clinically studied NMN Depends on precursor
NOVOS Boost is >99% pure NMN. The less than 1% of impurities are only nicotinamide, NR, and water. Purity varies across the category, and many products do not publish a figure at all. >99% NMN Often unspecified
Independent testing Lot-level results published Not published
Other ingredients No fillers Fillers & excipients

Results from human clinical studies.

As we age, our NAD+ levels decline by as much as

87% in organs like skin, from birth to middle age.1

01

NAD+ levels · Randomized human clinical study

2.6× higher

Blood NAD+ levels reached up to 2.6× baseline after 12 weeks of 250 mg daily NMN supplementation in older men.2

02

Physical performance · Randomized human clinical study

50% farther

Mean six-minute walking distance increased by up to 50% after 60 days of NMN supplementation.3

03

Metabolic health · Randomized human clinical study

25% improvement

A measure of skeletal-muscle glucose metabolism improved after 10 weeks of 250 mg daily NMN in the studied population.4

  1. Age-associated changes in oxidative stress and NAD+ metabolism in human tissue, PLOS ONE, 2012
  2. Chronic nicotinamide mononucleotide supplementation elevates blood NAD+ levels and alters muscle function in healthy older men, npj Aging, 2022
  3. The efficacy and safety of β-nicotinamide mononucleotide supplementation in healthy middle-aged adults, GeroScience, 2023
  4. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women, Science, 2021

Results are from independent studies of NMN or NAD+ biology, not studies of NOVOS Boost. Study products, doses, durations, populations, designs, and outcomes varied. “Up to” figures reflect the largest reported mean change in the cited study and do not represent the percentage of participants who experienced a benefit. Results may not apply to generally healthy adults or predict individual outcomes.

Boost one pathway.
Support all 12 with Core.

Pair NOVOS Boost with NOVOS Core for more comprehensive longevity support.

Feature This productNOVOS Boost The foundationNOVOS Core
What it is 250 mg ultra-pure NMN 12-ingredient daily longevity formula
What it supports NAD+, cellular energy, DNA maintenance, metabolic health All 12 Hallmarks of Aging
Research Published human studies on NMN Finished formula studied in randomized, placebo-controlled human clinical trial
Add NOVOS Core to your routine

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Real scientists. Real doctors.

NOVOS is built with guidance from scientists and physicians whose expertise spans aging biology, genomics, neurobiology, nutrition, and clinical medicine, including experts affiliated with leading research institutions like Harvard Medical School, MIT, and Salk Institute.

Scientific advisors: Dr. Pamela Maher (Salk Institute), Dr. J. Pedro Magalhães (Harvard Medical School), Dr. George Church (Harvard Medical School and MIT), Dr. Robert Lufkin (USC School of Medicine), Dr. Diogo Barardo (University of Singapore), Dr. Oliver Medvedik (Cooper Union), and Dr. Avi Rosenbaum (scientist and biotech consultant).

8 yrsof research
7scientists & MDs formulated
7whole formulation studies
400+ingredient studies
1,800+verified clinicians recommend
3rdparty-tested for purity & potency

NOVOS Available At

  • Mayo Clinic Store
  • Bumrungrad International Hospital
  • Erewhon
  • Equinox
  • Remedy Place
  • Four Seasons
  • Sunlife Organics
“NOVOS takes a disciplined, biology-first approach in a space that too often prioritizes hype over evidence.”
Dr. Doina Kulick, M.D.Lead Physician, Longevity Medicine · Mayo Clinic Arizona

Verified customer reviews.

4.9

Based on 1,119 ratings

· Amy

Keeps me full, feels "good"

Love these bars over all the other stuff out on the market. I feel good knowing the quality of the ingredients, and I really appreciate that they keep me full and energized. I am not a fan of the berry flavor – it's chalky and has a slight aftertaste. Peanut butter one is great.

· MA

Amazing

I have been taking Boost for over 1yr and noticed a rise in my energy after only a few months, then I began to notice a healthy change in my immune system, quality of sleep and overall appearance.

· Rick

Fantastic product and fantastic…

Fantastic product and fantastic customer service! I highly recommend the NOVOS line. I've been taking them for 6 months and can see (skin) and feel (energy levels, sense well being) the difference. Also, I prefer the Orange flavored Core vs the unflavored version.

· Martha Rooney

Novos Boost makes you feel younger and…

Novos Boost makes you feel younger and more energetic! Great products. Good service!

· Sol Vikström

Two years with novos

Me, 44yrs and my partner 56yrs have been taking core three times a week. + boost 5 times a week, pausing at weekends for two yrs now. We both have senior work titles with lots of cofnitive pressure, but we always have the energy to use our home gym each morning and almost never feel tired or sick. We are pescaterians. Highly recommend novos to anyone who cares to stay young at heart, body and mind 🙂 I take 500mg mg, my partner 750mg. If I go up more then this my rhr elevates by 10.

· Lisa H.

One month in

I’m coming up on my first month of core + boost—and it’s really already changing my energy levels. I just feel BETTER. I can’t wait to see the benefits at the 3,6, and 12 month mark!!

Individual experiences may vary and are distinct from results observed in controlled clinical research.

Everything you might want to know.

Conversion-ordered. Short answers, longer answers a tap away.

When will I feel results?
Some people notice changes in energy or recovery immediately, while other benefits may be subtle and build with consistent use over weeks to months. Human NMN studies have generally evaluated outcomes over several weeks to several months. Individual results vary.
What is NMN, and how does it support NAD+?
NMN, or nicotinamide mononucleotide, is a direct precursor your body uses to produce NAD+. NAD+ supports cellular energy production, DNA maintenance, metabolic health, and other essential cellular processes. NAD+ is not orally bioavailable for direct administration.
Is NOVOS Boost clinically studied?
NOVOS Boost itself has not been clinically studied. However, it is made with just one ingredient—NMN—an ingredient evaluated in multiple human clinical studies, including randomized, placebo-controlled trials.
How is NMN different from NR and other NAD+ precursors?
NMN is the direct precursor to NAD+. Earlier-stage precursors such as NR require an additional conversion step before becoming NMN and then NAD+. Both NMN and NR have been studied in humans, but NOVOS chose ultra-pure NMN for its direct role in NAD+ production.
How much NOVOS Boost should I take?
Take two capsules for 250 mg of NMN. This serving may be taken once or twice daily. Follow the product directions and speak with your healthcare professional before taking higher amounts.
When and how should I take it?
NOVOS Boost can be taken with or without food. Swallow the capsules with water, or open them and take the filler-free powder directly (e.g., under your tongue) or mix it into water. Consistency matters more than the precise time of day.
Why does NOVOS Boost use two capsules?
Two small capsules deliver a complete 250 mg serving while keeping the capsules easy to swallow. The formula contains NMN without added fillers or unnecessary excipients.
Why pair NOVOS Boost with NOVOS Core?
Boost provides focused NAD+ support through NMN. Core is a broader, 12-ingredient longevity formula designed around all 12 Hallmarks of Aging. They can be used together as complementary parts of a more comprehensive longevity routine.
Is NOVOS Boost safe with my medications or other supplements?
NMN has been well tolerated in published human studies, but individual circumstances differ. Consult your healthcare professional before use if you take medication, manage a medical condition, are preparing for surgery, or use other supplements that affect similar pathways.
Who should not take NOVOS Boost?
Do not use it if you are pregnant, nursing, under 18, or have been advised by a healthcare professional to avoid NMN. People with medical conditions or those taking medication should consult their healthcare professional before use.
How is NOVOS Boost tested?
NOVOS Boost is third-party tested for identity, purity, potency, and contaminants. Lot-level testing results are published so customers can review the quality of the product they receive.
How should I store NOVOS Boost?
No refrigeration is needed. Store it tightly closed in a cool, dry place away from heat, moisture, and direct light.
Can I cancel or pause my subscription?
Yes. You can pause, skip a delivery, or cancel anytime from your account. No phone calls, no lock-in.
Is NOVOS Boost HSA/FSA eligible?
Yes. NOVOS Boost may qualify for HSA/FSA reimbursement through our partner Truemed. Look for the Truemed option at checkout.
Where is it made?
NOVOS Boost is manufactured in the U.S.A. in cGMP facilities, using rigorously tested ingredients from trusted partners worldwide.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.

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Click-through evidence · Cellular energy and endurance

Cellular energy and endurance

NAD+ is the molecule your cells use to turn food into usable energy. Levels fall as we age. NOVOS Boost is made with human clinically studied NMN, which your body uses to support its own NAD+ production.

  • Human NMN research
  • 250 mg per serving
  • No caffeine, no stimulants

In a published human study of NMN supplementation, researchers observed that after 30 days, 67% of participants in the 600 mg and 900 mg groups showed measurable changes in walking distance (up to 38%); the trial also reported up to 50% improvement by day 60.

Published research on the NMN ingredient, not on NOVOS Boost, and conducted at daily doses of 600 mg to 900 mg. NOVOS Boost provides 250 mg per 2-capsule serving; recommended range 250 mg to 500 mg per day. Study population results are not a guarantee of individual outcomes. Individual results may vary.

Click-through evidence · DNA repair and cellular maintenance

DNA repair and cellular maintenance

NMN is a building block of NAD+, an important molecule that enzymes need in order to support healthy DNA, maintain the epigenome, and ensure cellular integrity.

  • Human NMN research
  • Telomere markers
  • 300 mg/day, 90 days

In a published human study of men aged 40 to 60, researchers reported significant changes in telomere-length markers in peripheral blood mononuclear cells at the 300 mg/day NMN dose over a 90-day observation period.

In a laboratory study conducted by Ichor Life Sciences, the combination of the ingredients in NOVOS Core and the NMN in NOVOS Boost showed an average 68% reduction in DNA oxidative damage from irradiation in human endothelial cells.

Published research on the NMN ingredient, not on NOVOS Boost. Single study, small sample size; replication pending. The Ichor study is an in vitro laboratory study; results may not translate to human outcomes. Individual results may vary.

Click-through evidence · Metabolic health

Metabolic health

NAD+ sits at the center of how cells sense and use nutrients. That machinery changes with age.

  • Human NMN research
  • 10 weeks
  • Older adults

In a human trial, NMN supplementation was associated with a 25% change in muscle insulin sensitivity markers after 10 weeks in older adults, along with enhanced metabolic signaling and physical activity.

Published research on the NMN ingredient, not on NOVOS Boost. Study population results are not a guarantee of individual outcomes. Individual results may vary.

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