The NOVOS Longevity System
You and your longevity stack deserve better.
Every supplement in your stack may have strong evidence behind it. The combination should too.
NOVOS Core combines 12 longevity ingredients in one Hallmarks-based formula studied in a randomized, double blind, placebo controlled human trial.
What happens when longevity compounds are combined?
61%
of combinations delivered the same or worse result than the best-performing ingredient on its own.
15%
of combinations shortened lifespan.
Based on a series of animal lifespan experiments in which longevity-enhancing compounds were administered in isolation and in combination.
Randomized human clinical trial — NOVOS Core
NOVOS Core improved blood vessel function, arterial flexibility and systolic blood pressure versus placebo.
- Randomized
- Double-blind
- Placebo-controlled
- 6 months
- Adults 40+
Blood vessel function (FMD)
+2.9% vs placebo
Flow-mediated dilation (FMD) at six months
Arterial flexibility (PWV)
1.18 m/s vs placebo
Pulse wave velocity (PWV) — lower is better
Systolic blood pressure
−6.1 mmHg vs placebo
For blood pressures already in normal range
Study independence
Conducted by University of Surrey researchers. Trial pre-registered at ClinicalTrials.gov. Senior author Professor Christian Heiss retained control over the data and publication decisions.
61 randomized / 43 completed · SSRN preprint · Manuscript under peer review
Why evidence level matters, Human clinical: Randomized or controlled human research supporting the specific claim.
Why should I take it?
A stack clinically studied as a true longevity formula — not a single ingredient with a story attached.
NOVOS Core was studied in a randomized, double-blind, placebo-controlled human trial and shown to support biological systems predictive of lifespan and healthspan. That is the long game. In the short term, people most often notice changes in how they sleep, think, and feel.
Sleep
Support for deeper, more restorative sleep as your routine settles in.
Energy
Steadier day-to-day energy rather than a stimulant spike and crash.
Mood
A calmer, more even baseline reported through the first months of use.
Cognition
Sharper focus and mental clarity across a normal working day.
Skin
Support for firmness and hydration as skin biology is supported from within.
No two people react precisely the same way to nutritional interventions. Individual results will vary with some obtaining no benefit. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
81% reported feeling a difference.*
Better sleep was one of the most commonly reported benefits.
*Based on a self-reported NOVOS Core customer survey two weeks post-purchase. Individual results may vary.
Put a clinically tested formula at the center of your longevity protocol.
- Vitamin C
- 100 mg
- Magnesium
- 304 mg
- Glycine
- 2,000 mg
- Calcium Alpha-Ketoglutarate
- 1,100 mg
- GreenGrown® Glucosamine Sulfate
- 1,000 mg
- Rhodiola Rosea Root Extract
- 300 mg
- L-Theanine
- 150 mg
- Hyaluronic Acid
- 100 mg
- Fisetin
- 100 mg
- Organic Ginger Root Extract
- 100 mg
- Pterostilbene
- 50 mg
- Lithium Aspartate
- 20 mg
Every ingredient and finished product is tested for purity and contaminants. Every batch is independently verified for quality, purity and potency.
- Heavy Metal Tested
- Microbiological Screened
- Allergen Verified
- Shelf-Stability Validated
- GMP-Certified Facility
- USP-Grade Ingredients
Your current stack
Put NOVOS Core next to what you already take.
Compare the ingredients. Compare the doses. Compare the evidence behind the combination.
Approximately 2 to 5 times greater effect in support of healthy endothelial function than the most effective studied supplements (polyphenols, cocoa, and beet root).
No two people react precisely the same way to nutritional interventions. Individual results will vary with some obtaining no benefit.
References: Heiss C. et al., randomized double-blind placebo-controlled NOVOS Core trial (University of Surrey, SSRN preprint, 2025); Heiss C. et al., Flavanols and cardiovascular function, Am J Clin Nutr; Hobbs D.A. et al., Dietary nitrate (beetroot) and vascular function, Br J Nutr.
The NOVOS System
Take your longevity protocol further.
The randomized human trial evaluated NOVOS Core.
NOVOS Age
Track changes in your aging biology.
Biological Age. Pace of Aging. 11 Organ Ages. Telomere Length.
Establish a baseline with one at-home blood sample. Retest over time.
Hold your stack to a higher standard.
Start with NOVOS Core.
Questions
Longevity supplements, answered.
How is NOVOS Core different from taking individual longevity ingredients?
NOVOS Core is one formula of 12 ingredients designed around the Hallmarks of Aging, and the complete formula was evaluated in a randomized, double blind, placebo controlled human study.
Has NOVOS Core been studied in humans?
Yes. A randomized, double blind, placebo controlled study at the University of Surrey randomized 61 apparently healthy adults aged 40 and older; 43 completed six months. The primary endpoint was flow-mediated dilation. The manuscript is a preprint and has not yet completed peer review.
Why does finished-formula testing matter?
Published research on combinations of longevity compounds found that 61% performed no better than the strongest single ingredient, and 15% reduced lifespan.
Can NOVOS Core fit into an existing supplement stack?
Every dose is disclosed, so you can review the formula against what you already take. Discuss changes with your healthcare provider, particularly if you take medication.
What does NOVOS Age measure?
Biological Age, Pace of Aging (DunedinPACE), 11 Organ Ages and Telomere Length, from one at-home blood sample.