Calm
Stay composed
Support a healthy response to everyday stress, without positioning the formula as a sedative.
Stay sharp without living in overdrive.
Calm focus, stress resilience and recovery, in one daily 12-ingredient longevity formula.
4.8 · 3,000+ reviews
Over 15 million doses served · Recommended by 2,000+ doctors & clinicians
— Award Winning Formulation —
Trusted by clinicians and sold at some of the world’s most discerning retailers.
Join 50,000+ people investing in their longevity
Mayo Clinic, Mayo Clinic Store, Bumrungrad International Hospital, Erewhon, Equinox, The Four Seasons, and Sunlife Organics are trademarks of their respective owners. Retailer availability does not constitute endorsement of any particular positioning or claim on this page.
Developed with scientists and physicians from Harvard, MIT, Salk and other leading institutions.
A daily foundation for high-pressure lives
Not another stimulant.
A different kind of daily support.
NOVOS Core combines ingredients selected for calm attention, stress adaptation, mental stamina and recovery with a broader longevity formulation targeting the biological processes involved in healthy aging.
Calm Focus
Healthy Stress Response
Mental Stamina
Restful Recovery
Whole-Body Longevity
MonthlySave 10%
6 MonthsSave 15%
AnnualSave 27%
One-TimeNo subscription
One drink pack daily · Free shipping on subscriptions · Pause, skip or cancel anytime
Available in Orange, Tropical Passion and Unflavored.
The modern performance problem
You don’t always need more stimulation.
You need better regulation.
Stress is a normal biological response. In the right amount, it helps us respond to challenges. But when mental demands remain high, the brain systems responsible for working memory, flexible thinking and executive control can become less effective.
The goal isn’t to eliminate stress. It’s to stay more resilient when it arrives, and recover when the demand is over.
Focus
Stay mentally present
Support the attention and executive processes needed to think clearly when demands are high.
Recover
Be ready again tomorrow
Restorative sleep and overnight recovery help support next-day mental and physical function.
References: Shields GS, et al. Neuroscience & Biobehavioral Reviews. 2016 · Girotti M, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2018. This describes the biology of stress. It is not a claim that NOVOS Core reverses these effects.
Calm shouldn’t mean checked out.
The ideal state isn’t sleepy. And it isn’t overstimulated. It’s calm enough to think clearly, alert enough to perform, and resilient enough to recover.
← Sedated
Flat. Slowed down. Present but not really here.
Calm + Clear
★ Ideal · NOVOS Core
Steady enough to think. Alert enough to perform.
Overstimulated →
Wired, scattered, and paying for it later.
No caffeine. Designed for daily use without adding another source of caffeine to your routine.
L-Theanine
Calm attention
150 mg
Rhodiola Rosea
Stress adaptation + stamina
300 mg
Magnesium
Nerve function + cellular energy
304 mg
Glycine
Recovery support
2,000 mg
Centered on calm focus + stress resilience · + 8 additional longevity ingredients
12 ingredients. One daily longevity drink.
Calm focus, stress resilience and recovery are built into NOVOS Core on purpose. What makes Core different is that those ingredients sit inside a complete longevity formulation, so the same daily drink that helps you stay composed today is also working on the biology of how you age.
Calcium Alpha-Ketoglutarate
1,100 mg
Cellular metabolism
Glycine
2,000 mg
Recovery support
Pterostilbene
50 mg
Cellular signaling
Fisetin
100 mg
Cellular housekeeping
Magnesium
304 mg
Nerve function · as Magnesium Malate · 72% DV
GreenGrown® Glucosamine Sulfate
1,000 mg
Joint & metabolic support
L-Theanine
150 mg
Calm attention
Rhodiola Rosea Root Extract
300 mg
Stress adaptation · 3% rosavins, 1% salidrosides
Hyaluronic Acid
100 mg
Tissue hydration
Vitamin C
100 mg
Antioxidant support · 111% DV
Organic Ginger Root Extract
100 mg
Whole-body support · 2% gingerols
Lithium Aspartate
20 mg
Trace mineral
Randomized · Double-Blind · Placebo-Controlled
Most supplement formulas cite ingredient studies.
NOVOS Core clinically studied the actual formula.
The complete NOVOS Core formulation was evaluated in a 6-month randomized, double-blind, placebo-controlled human clinical trial at the University of Surrey in healthy adults aged 40+.
Randomized
Double Blind
Placebo Controlled
Finished Formula
n = 61
6 Months
Endothelial function
+2.9%
improvement at six months vs. placebo
Arterial flexibility
1.18 m/s
improvement in pulse wave velocity vs. placebo
Healthy blood pressure
−6.1 mmHg
systolic blood pressure in adults already within the normal range
Head-to-head comparisons
How NOVOS Core compares to leading interventions studied in similar populations
Results compared against published meta-analyses and randomized controlled trials of exercise, diet and supplements in similar populations.
Sustained FMD improvement (%)
Each 1% improvement in FMD has been associated with lower future cardiovascular risk in epidemiological studies.
PWV improvement (m/s)
Arterial flexibility typically worsens by roughly 1 m/s per decade.
SBP reduction (mmHg)
These reductions occurred in adults already within the normal blood pressure range.
Effect sizes are based on published clinical trials and meta-analyses reporting changes in similar biomarkers in adult populations. The NOVOS Core trial measured cardiovascular markers only; it did not evaluate stress, mood, focus, cognition or sleep.
Manuscript under peer review. Trial registration: ClinicalTrials.gov NCT06145087.
Self-reported customer experience
What customers say they notice.
81%
of surveyed NOVOS customers reported feeling a difference within two weeks across one or more areas of daily well-being, including energy, sleep, mood, cognition, skin and overall well-being.
Self-reported customer survey. This does not mean 81% experienced a specific calm, mood or focus benefit. Individual experiences vary and are distinct from controlled clinical research.
“I feel more energized and focused throughout the day. It has become part of my morning without me having to think about it.”
“I've noticed increased mental clarity since starting NOVOS Core.”
“I sleep well, wake up refreshed, and have more energy through the day.”
“My ability to think and organize has improved since I began taking it daily.”
A focus supplement only addresses today.
Core was designed for today + tomorrow.
Many focus products
- One immediate goal
- Often caffeine- or stimulant-centered
- Usually one or a few actives
- Typically no finished-formula clinical trial
NOVOS Core
- Calm-focus ingredients
- No caffeine
- Stress-adaptation ingredients
- Recovery-support ingredients
- 12-ingredient healthy-aging system
- Finished formula evaluated in a randomized human clinical trial (cardiovascular endpoints)
One minute for the next 24 hours, and the years ahead.
Mix one drink pack into water once a day. Most customers take Core in the morning, although some prefer evening use. Consistency matters more than the time of day.
Sugar Free
Vegan
Gluten Free
No Caffeine
Third-Party Tested
No Proprietary Blend
Every Dose Disclosed
Built by longevity scientists, not trend marketers.
Developed with guidance from scientists and physicians whose expertise spans aging biology, genomics, neurobiology, nutrition and clinical medicine.
Listing an advisor does not imply they personally formulated Core or endorse any specific claim on this page.
A calmer mind. A stronger foundation.
Make resilience part of your daily routine.
L-Theanine. Rhodiola. Magnesium. Glycine. Plus the rest of NOVOS Core’s 12-ingredient longevity system, in one sachet a day.
NOVOS Core · Orange
30 daily drink packs
- No caffeine · no stimulant spike
- Every dose disclosed · no proprietary blends
- Third-party tested
- Free shipping on subscriptions
Flavor
Plan
6 Months · Orange
$93
per box · billed every 6 months · about $3.10/day
Start NOVOS CorePause, skip or cancel anytime · Free shipping on subscriptions
Not ready? Try all 3 flavors: Sample Pack, $15.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Questions, answered plainly.
Is NOVOS Core an anxiety supplement?
No. NOVOS Core is a longevity dietary supplement designed to support normal biological functions, including ingredients selected for calm focus, healthy stress response and recovery. It is not intended to diagnose or treat anxiety disorders or any psychiatric condition.
Will NOVOS Core make me sleepy?
NOVOS Core is not designed as a sedative. It contains no caffeine and combines ingredients selected for calm focus, stress adaptation and recovery. Individual responses vary, and some customers prefer taking Core in the morning while others take it later in the day.
Can NOVOS Core help me focus?
NOVOS Core contains 150 mg of L-Theanine and 300 mg of standardized Rhodiola Rosea. Human studies of these ingredients have examined selected aspects of attention, mental fatigue and performance under stressful conditions. NOVOS Core itself has not been clinically tested for focus or cognition.
Is NOVOS Core clinically studied?
Yes. The complete NOVOS Core formula was studied in a randomized, double-blind, placebo-controlled human clinical trial in adults aged 40+. The measured outcomes were cardiovascular aging markers, including endothelial function and arterial flexibility. Stress, mood, focus, cognition and sleep were not endpoints in that clinical trial.
How much L-Theanine is in NOVOS Core?
150 mg per daily serving. Human studies of L-Theanine have used a range of doses. Several stress studies used approximately 200 mg, while selected attention studies have examined doses starting around 100 mg.
How much Rhodiola is in NOVOS Core?
300 mg of Rhodiola Rosea root extract per serving, standardized to 3% rosavins and 1% salidrosides. Human Rhodiola studies have used differing extracts and doses, so ingredient research should not be interpreted as a clinical study of NOVOS Core itself.
How much magnesium is in NOVOS Core?
304 mg of magnesium, equal to 72% of the Daily Value, provided as Magnesium Malate. Magnesium supports normal nerve and muscle function and cellular energy metabolism.
Why is there glycine?
Core provides 2 g of glycine. Glycine participates in numerous biological processes and has also been studied in connection with sleep and next-day recovery. Small human sleep studies generally used approximately 3 g, so these studies are not dose-matched clinical evidence for Core.
Why does NOVOS Core contain lithium?
NOVOS Core contains 1 mg of elemental lithium, provided as lithium aspartate. Lithium occurs naturally in food and water. This is a trace nutritional amount far below prescription lithium dosing. Research into trace lithium and long-term brain health remains emerging, and Core should not be viewed as a substitute for prescription lithium or any psychiatric treatment.
Can NOVOS Core treat anxiety or depression?
No. NOVOS Core is not intended to diagnose, treat, cure or prevent anxiety, depression, bipolar disorder or any other disease or psychiatric condition. Anyone experiencing significant or persistent anxiety, depression or other mental-health symptoms should speak with a qualified healthcare professional.
Can I take NOVOS Core with psychiatric medication?
Because Core contains multiple bioactive ingredients, including Rhodiola and a trace amount of lithium, anyone taking prescription psychiatric medication or other medications should discuss use with their healthcare professional or pharmacist before starting Core.
When should I take Core?
Once daily. Most customers use it in the morning, while some prefer later in the day. Individual responses vary and consistency is more important than a specific time.
Calm focus · Whole-body longevity
Stay sharp without living in overdrive.
Support calm focus, stress resilience, recovery and healthy aging with one daily 12-ingredient longevity formula.
From approximately $2.63/day on the annual plan · Free shipping · Pause or cancel anytime