NOVOS Age
The most advanced biological aging test available
Track your pace of aging and learn about the impacts of lifestyle changes. Includes comprehensive guidance on how to improve your scores with lifestyle upgrades.
With the best-in-class NOVOS Age, gain a deeper understanding of how your longevity lifestyle is impacting how fast – or slow – you’re aging.
Powered by the 3rd (latest) generation DunedinPACE Rate of Aging Clock, NOVOS Age is a critical component of your longevity journey, providing you the insights and tools you need to be Younger For Longer. You’ll learn how much you are aging per year, which will help you understand your overall health better than any other blood biomarker.
The accompanying NOVOS Age report provides you with actionable guidance on how to improve your results through lifestyle changes.
Each NOVOS Age kit includes:
- DunedinPACE epigenetic clock to measure your rate of aging
- Latest generation clock, backed by 45+ publications at 30+ scientific labs
- Clock created by Columbia University & Duke University biological clock scientists
- Blood sample collected by simple prick of the finger
- Comprehensive 55 page report, including guidance on improving your Rate of Aging
- Bonus Tests: Biological Age and Telomere Length
$349 for one or $299 per kit for orders of two or more. Currently ships within the US and Canada only.
Pace yourself
The Key to Unlocking Longevity
Test
Take our at-home test by simply pricking your finger to collect a blood sample. Mail your sample to our lab to get your results in about 4 weeks.
Understand
Receive your comprehensive NOVOS Age report, primarily focused on the most powerful epigenetic test – your Pace of Aging – and providing you with actionable longevity insights.
Optimize
With NOVOS, learn how to maintain or improve your results through lifestyle interventions. NOVOS Core and NOVOS Boost are a great place to start, and you can leverage the many free resources we offer.
Retest
We encourage you to retest your epigenetic age regularly (e.g., every 12 months). This can help you measure your progress and give you insights into which lifestyle changes are moving you in the right direction.
Pace of Aging
Powerful longevity insights
Understand How Fast You’re Aging
The NOVOS Pace of Aging shows you if you are slowing or accelerating your aging.
Using The DunedinPACE Rate of Aging Clock
Developed by scientists from Duke & Columbia University, and backed by 45 scientific papers.
We cover every dimension that matters when considering biological age clocks here and we encourage you to compare.
With a Simple At-Home Test
With blood collected through a small prick of the finger, our team of scientists extracts and epitypes your DNA.
WITH EVERY TEST
The NOVOS Age Report
Built around your Rate of Aging, the NOVOS Age report is the starting point of your Longevity Journey.
The report is filled with robust scientific information, compelling longevity insights, like your Biological Age and Telomere Length, as well as actionable recommendations to help you be Younger For Longer.
Prolong your lifespan with our expertise
Our world-renowned team of longevity scientists and doctors developed innovative supplements to slow your aging and unlock your vitality. With ongoing, cutting-edge research, we continue to offer you new possibilities.
“I’m impressed by… how they approach aging as a complex phenomenon — aiming at all pathways and hallmarks of aging simultaneously.”
Dr. George Church, PhD — Harvard Medical School & MIT Professor
“What really impressed me about NOVOS was the comprehensiveness of their analysis of aging research to design their product.”
Dr. Pamela Maher — University of British Columbia
“The NOVOS formulation is informed by science and is the current state-of-the-art in longevity supplements.”
Dr. J. Pedro Magalhães — Harvard Medical School
“NOVOS Core… has been reviewed by scientists within the aging research community to ensure the most effective and safest ingredients.”
Dr. Oliver Medvedik — Harvard Medical School
NOVOS Age: Published, Precise and Controlled
Publication
NOVOS Age uses the DunedinPACE clock, developed by Columbia University and Duke University researchers, which as of April 2023 has 45 scientific papers published from 30+ independent research labs.
Precision
The intraclass correlation (ICC) value is how testing precision is measured. NOVOS Age is optimized to be reliable across repeat measurements, with published and peer-reviewed best-in-class ICC values (accuracy) >0.96 for all three algorithms.
Control
If a test does not control for cell types found in the sample, it means that there can be large variations for a single person throughout the course of the day. NOVOS Age uses Published and Patented Advanced 12-cell immune deconvolution methods.
NOVOS Age vs. Other Biological Age Clocks
| Attribute | NOVOS Age Clock | Saliva-based Clock by Celebrity Scientist's New Startup | Other tests |
|---|---|---|---|
| Tissue Collection | Blood from a small poke of a finger, a method that is more accurate than via saliva | Saliva from a cheek swab, a method that is generally not very accurate | Blood collection methods that are invasive and far more uncomfortable that via small pokes of fingers |
| Sample Size | Samples from more than 20,000 humans | Samples from more than 8,000 humans | Samples typically from fewer than 2,500 humans |
| DNA Methylation Technology | Built using the modern MethylationEPIC array that measures 850,000 DNA sites and tests your sample on that same technology | Built using the modern MethylationEPIC array that measures 850,000 DNA sites but does not test your sample on that same technology | Built using older arrays that only capture 27,000-450,000 DNA sites |
| Chronological Age Range | 8-102 years | 18-100 years | Less expansive age range often lacking individuals 90+ years of age |
| Diversity | Significant diversity across ethnicity, race, and sex, all supported by many peer reviewed publications | Diversity across ethnicity, race, and sex, but without support of peer reviewed publications | Insufficient representation across ethnicity, race, and sex and without support of peer reviewed publications |
| Test Reliability | Optimized to be reliable across repeat measurements, with published and peer reviewed best-in-class ICC values (accuracy) >.96 for all three algorithms | Claims of being optimized to be reliable across repeat measurements without disclosing ICC values | Exhibit high test-retest error rates |
| Model Type | 3rd generation (latest) clock, the only one trained on longitudinal analysis (people across their lifetimes), the best way to track biological age as shown in publications and tested via peer review | Self-claimed "novel" method-based model that lacks publications, peer review, and head-to-head comparisons against other clocks | 1st generation (oldest) model trained to simply estimate chronological age instead of biological aging |
| Outputs and Analysis | Three: 1) 3rd generation Pace of Aging via DunedinPACE, 2) Biological Age, and 3) Telomere Length | One: A less accurate output of biological age | A single, less accurate output of biological age |
| Creators of Clock | A top team of Duke University and Columbia University scientists with peer reviewed publications | A start up company without publication of the algorithms, thus lacking scientific scrutiny | |
| Number of Studies | 45+ published studies by 30+ longevity scientists' labs across the world | Zero published studies | |
| Immune Cell Controls | Published and Patented Advanced 12-cell immune deconvolution methods (cell changes won't impact accuracy, which is common in saliva and makes blood samples better) | No controls | No controls |
| Studies that prove accuracy in different ethnic groups | Algorithms validated in the Family and Community Health Study of African American Families study, MESA (Multi-ethnic Study of Atherosclerosis), Cebu Longitudinal Health and Nutrition Survey (CLHNS Phillipines), Northern Finland Birth Cohort 1966 Study, Health and Retirement Study, the Normative Aging Study, the Framington Heart cohort, TILDA (the Irish Longitudinal Study of Aging), and many more. | No studies | No studies |
| Studies that show relatonship to outcomes | Algorithms have been validated in the Health and Retirement Study, the Normative Aging Study, the Framington Heart cohort and more. | No studies | No studies |
| Studies that show change with validated anti-aging interventions | The only algorithm proven to respond in a significant way to validated anti-aging interventions such as caloric restriction (Published in Nature) | No studies | No studies |
| Include Clinical Covariates | 21 clinical covariates and telomere length | No clinical covariates | No clinical covariates |
| Comparisons to other algorithms | Comparisons in the FHS study and in the Health and Retirement Study show superior results | No published comparisons | No published comparisons |
| Shares actual data on precision (ICC values) | See ICC values with comparisons in the FHS study. | No data | No data |
The DunedinPACE Rate of Aging Clock that we offer in NOVOS Age is the most advanced epigenetic clock on the market, and is the most accurate way currently available to detect changes to your biological aging. In fact, the innovative algorithms use machine learning to improve. That means, each time you test, the clocks become increasingly accurate.
By tracking your rate of aging, you’ll be able to see how your lifestyle is impacting your biological age in significantly less time than by looking at your biological age: it is more sensitive to change, and changes more quickly.
During your Longevity Journey, NOVOS will provide you with valuable information and insights on how to slow your aging process. This epigenetic aging report is a great and important start.
Take It A Step Further
The ultimate longevity regimen.
NOVOS is the only solution designed to address the 12 scientifically proven root causes of aging and shown to slow down your pace of aging.
Leverage AI to visually measure your facial age.
Find out if your lifestyle choices are impacting your facial age, and keep testing to track the progress as you make improvements.
Find out if your lifestyle is optimized for longevity.
Take this quiz to assess if you’re maximizing your healthspan & lifespan potential.
Frequently asked
Two general categories of biological age tests exist:
– Tests that measure your rate of aging
– Tests that measure your biological age
Tests that measure your rate of aging determine how fast you are aging.
Tests that measure your biological age determine how old you are biologically.
You can compare the rate of aging to how fast a clock is ticking (how fast you are aging), and you can compare biological age to the time a clock displays (how old you really are).
Changing the speed that the clock is ticking can be noticed in significantly less time than seeing change in a clock that has been ticking for decades. This is one of the multiple reasons we emphasize the Rate of Aging clock as the primary focus of Age (80% of the emphasis should be on this clock).
Biological age tests can be based off of the epigenome, proteome, microbiome, and more. Certain epigenetic tests are among the most accurate of all biological age tests, which is why NOVOS decided to offer these tests over alternatives.
To that point, there are already many epigenetic clocks in existence, and some are better than others.
Most epigenetic clocks measure biological age, to varying degrees of accuracy; very few of them measure the rate of aging.
The DunedinPACE rate of aging clock is currently considered by many in the field to be the most relevant and accurate test available with regards to mortality and disease risk.
It’s also the most actionable, since its outputs are based on your current lifestyle.
These are some of the reasons that we chose to offer the DunedinPACE clock to our customers.
Your rate of aging is a measurement of how fast you age. It calculates how much you age biologically for each chronological year.
The lower the value, the better.
An average rate of aging would be a rate of one biological year for every chronological year you aged. If your rate of aging is lower than 1, you age slower than average.
For example, if your rate of aging is 0.9, you only aged 0.9 years biologically for each chronological year that passed, or 10% slower than average.
If your rate of aging is higher than 1, you age faster than an average person would be expected to age.
For example, if your rate of aging is 1.2, you age biologically 1.2 years for each chronological year that passes, which is 20% faster than normal.
You want your rate of aging to be below 1; this means you’re aging more slowly than normal.
The epigenetic rate of aging clock NOVOS uses has been developed by scientists from Duke University and Columbia University. The clock is called DunedinPACE. Multiple studies have been published about the DunedinPACE clock, including comparisons against other well-regarded epigenetic tests, in which DunedinPACE proved to be even more accurate.
Many experts in the field believe that DunedinPACE is currently the best clock available to measure your rate of aging.
Besides the Rate of Aging clock, NOVOS Age also includes a biological age clock.
The biological age clock determines how old you are biologically.
If you are biologically older than your chronological age, this implies you have aged faster over the course of your lifetime.
As a result, you could be at a higher risk of dying compared to someone with a lower biological age, or you could be at a higher risk of getting aging-related diseases and symptoms.
We emphasize risk, because we’re dealing with statistical probabilities. This risk can also be offset by making improvements to your lifestyle, via diet, activity, supplementation, sleep, stress management, etc., which we cover in our blog.
If your biological age is lower than your chronological age, this implies you have aged more slowly over the years.
You could therefore have a lower risk of dying than someone with a higher biological age, or have a lower risk of aging-related diseases and symptoms.
It’s important to note that changes to your biological age will be more gradual than changes to your pace of aging, because the pace of aging measures your current speed, whereas your biological age measures a historical lifetime of aging.
Some may see changes in their biological age – either positive or negative – in very short timeframes (i.e., if they test every few weeks or months). These changes are most likely predominantly based on the error margins of the test and should not be interpreted literally.
Biological age tests are best looked at over the course of a year or more. You should accumulate a few results to see the overall trend relative to your chronological age.
In the meantime, focusing on your pace of aging will give you the appropriate guidance to know that what you’re doing is working.
The DunedinPACE clock is one of the most accurate epigenetic clocks. Nonetheless, it can be difficult to measure the impact of any single intervention, given the innumerable lifestyle factors that may counteract the positive effects on the clock.
For example, taking a supplement or exercising may have a positive impact on the clock that may be counteracted by other lifestyle variables (e.g., stress, sleep, diet, overindulging as a reward for exercising, other supplements, your microbiome, infections or activation of the immune system). In such a case, the net result is neutral or negative, meanwhile the wrong conclusion may be drawn – that the supplement or exercise did not confer any benefits.
This is even more the case for the biological age clock, which measures many forms of accumulated damage and lifestyle interventions you underwent throughout your life (including factors you were exposed to decades ago).
Using this clock to measure whether one intervention (e.g., exercising more) changes the clock will be difficult in the short-term, given the clock is, in most cases, currently not accurate enough on an individual level (some studies, using dozens or hundreds of participants, can find effects of one or multiple interventions).
Therefore, use the biological age clock to get an overview of all lifestyle interventions and habits accumulated over a lifetime.
Use the rate of aging clock to get a general overview of your health and how fast you are aging right now, being mindful of the innumerable lifestyle and (epi)genetic factors that are playing a role.
We help you keep track of confounding factors by providing you with a short survey for you to complete with each NOVOS Age test. This will enable you to compare your lifestyle changes between tests in a more precise way than relying on your memory, and may help you make sense of your results.
Ideally, you get tested every year, at the same time, to minimize seasonal confounding factors and to have an insight on how you’re faring on your Longevity Journey.
We encourage you to retest your epigenetic age regularly (e.g., every 12 months), and not to expect changes too soon. However, what if you were biologically younger during one test and now older after retesting? Or vice versa?
This result can be due to the change being within the margin of error of the test. So, if it’s plus or minus one to two years, consider this to be a possible explanation. Additionally, there may be lifestyle factors that impacted your results that you may not be fully aware of.
It’s possible that in the time between two tests, you were exposed to factors that accelerated or decreased your aging rate or biological age. For example, psychological or physical stress, alcohol consumption, dietary patterns (what, when and how much you eat), activity types and levels, time spent in green spaces and sun exposure, air pollution and smoking or vaping, supplements or prescriptions, etc.
Ideally, you continue to test yourself over the long term to see the trend and to discover what lifestyle approaches work best for you on your Longevity Journey.
Epigenetic clocks are becoming increasingly accurate, trained on larger and more specific data sets.
NOVOS will update its clocks as they evolve and adequate research supports their value, so that we can offer you the best science-based, validated clocks available to assess your health and biological age.
Telomeres are the endcaps on your chromosomes that serve to protect your DNA. With each cell division, and with age, your telomeres shorten.
Once thought of as holding promise to possibly determine one’s biological age, scientists have since found that the range of telomere length is too wide given one’s age. Further, telomere length doesn’t predict disease risk or mortality – that is, until they become too short.
Telomeres can also be protected so that they shorten more slowly; they can also be lengthened. For example, certain ingredients in NOVOS Core, like pterostilbene, magnesium and lithium, have been found to have these favorable effects.
With this in mind, you should look at your telomere length as a biomarker that is relevant to understanding your overall aging process, but you should not look at it for your biological age. Specifically, if your telomere length is very short for your age, consider ways to slow down or reverse its shortening.
Currently, epigenetic clocks are arguably the best tools to paint a holistic picture of your health, aging, and longevity.
Regularly testing your epigenetic rate of aging and biological age (e.g., every 12 months) can help you to assess your health and longevity potential. It can also give you insights into which lifestyle changes are moving you in the right direction.
The lower your epigenetic rate of aging and biological age, the healthier you are, and the lower your mortality risk.
Go to novoslabs.com/registerage to register your kit. Use your kit’s bar code and complete your 5 minute health assessment.
Tips: Write down your barcode number for future reference.
Don’t forget, we are unable to process your sample until it is registered and your online health assessment is completed.
You’ll receive an email when the lab receives your sample. Your results will be ready 2-4 weeks after that date.
Once your results are ready, you will be able to access them by signing into your secure online account.
- Blood spot card
- Lancets
- Alcohol wipe
- Gauze pad
- Bandage
- Biohazard bag
- Prepaid return envelope
- Instruction manual
- Insert
For NOVOS Age, due to the nature of the product, all sales are final. Currently, we only ship in the United States. Please be sure that your shipping address is accurate before submitting your order.
No, we do not ship NOVOS Age outside of the United States at the moment. You can purchase NOVOS Core and NOVOS Boost in many non-US countries.
Yes. While you can’t change the number of birthdays that have passed (chronological age), science has proven it is possible to slow down or accelerate your biological age based upon lifestyle changes.
