NOVOS Age - DunedinPACE Epigenetic Test Studies

No.	Publication Year	Researchers	Study	Data Set
1	2023	Yu, Y.-L.	Current Marital Status and Epigenetic Clocks Among Older Adults in the United States: Evidence From the Health and Retirement Study. Journal of Aging and Health, 35(1–2), 71–82. https://doi.org/10.1177/08982643221104928	The US Health and Retirement Study
2	2023	Caro, Juan Carlos, Cyrielle Holuka, Giorgia Menta, Jonathan D. Turner, Claus Vögele, Conchita D’Ambrosio,	Children’s internalizing behavior development is heterogeneously associated with the pace of epigenetic aging, Biological Psychology, Volume 176, , 108463, https://doi.org/10.1016/j.biopsycho.2022.108463.
3	2023	R Waziry, DL Corcoran, KM Huffman, MS Kobor, M Kothari, VB Kraus, WE Kraus, DTS Lin, CF Pieper, ME Ramaker, M Bhapkar, SK Das, L Ferrucci, WJ Hastings, M Kebbe, DC Parker, SB Racette, I Shalev, B Schilling, DW Belsky	Effect of Long-Term Caloric Restriction on DNA Methylation Measures of Biological Aging in Healthy Adults: CALERIE™ Trial Analysis. medRxiv 2021.09.21.21263912; doi: https://doi.org/10.1101/2021.09.21.21263912	CALERIE Trial
4	2022	Raffington, L., Tanksley, P. T., Sabhlok, A., Vinnik, L., Mallard, T., King, L. S., Goosby, B., Harden, K. P., & Tucker-Drob, E. M.	Socially Stratified Epigenetic Profiles Are Associated With Cognitive Functioning in Children and Adolescents. Psychological Science, 0(0). https://doi.org/10.1177/09567976221122760	Texas Twin Study
5	2022	Etzel, L, et al. Shalev, I.	Obesity and accelerated epigenetic aging in a high-risk cohort of children. Scientific Reports. 12,	The Child Health Study
6	2022	Kuzawa CW, Ryan CP, Adair LS, Lee NR, Carba DB, MacIsaac JL, Dever K, Atashzay P, Kobor MS, McDade TW.	Birth weight and maternal energy status during pregnancy as predictors of epigenetic age acceleration in young adults from metropolitan Cebu, Philippines. Epigenetics. 2022 Nov;17(11):1535-1545. doi: 10.1080/15592294.2022.2070105	Cebu Longitudinal Health and Nutrition Survey (CLHNS Phillipines)
7	2022	Freni-Sterrantino A, Fiorito G, D'Errico A, Robinson O, Virtanen M, Ala-Mursula L, Järvelin MR, Ronkainen J, Vineis P.	Work-related stress and well-being in association with epigenetic age acceleration: A Northern Finland Birth Cohort 1966 Study. Aging (Albany NY). Feb 2;14(3):1128-1156. doi: 10.18632/aging.203872.	Northern Finland Birth Cohort 1966 Study
8	2022	Botong Shen, Ph.D.1, Nicolle A. Mode, M.S.1, Nicole Noren Hooten, Ph.D.1, Natasha L. Pacheco Ph.D.,1, Ngozi Ezike, M.D.1, Alan B. Zonderman, Ph.D.1, and Michele K. Evans, M.D.	Association of race and poverty status with a faster pace of biological aging.	The HANDLE Study (NIA intramural study of older adults)
9	2022	Kim Y, Huan T, Joehanes R, McKeown NM, Horvath S, Levy D, Ma J.	Higher diet quality relates to decelerated epigenetic aging. Am J Clin Nutr;115(1):163-170. doi: 10.1093/ajcn/nqab201.	The Framingham Offspring Study.
10	2022	Simons, Ronald L., Mei Ling Ong, Man-Kit Lei, Eric Klopach, Mark Berg, Yue Zhang, Robert Philibert, Frederick X. Gibbons, Steven R.H. Beach	Shifts in lifestyle and socioeconomic circumstances predict change—for better or worse—in speed of epigenetic aging: A study of middle-aged black https://doi.org/10.1016/j.socscimed.2022.115175, Social Science & Medicine, Volume 307, 2022, 115175,	The FACHS Study
11	2022	Beach, S.R.H.; Klopack, E.T.; Carter, S.E.; Philibert, R.A.; Simons, R.L.; Gibbons, F.X.; Ong, M.L.; Gerrard, M.; Lei, M.-K.	Do Loneliness and Per Capita Income Combine to Increase the Pace of Biological Aging for Black Adults across Late Middle Age? Int. J. Environ. Res. Public Health 2022, 19, 13421. https://doi.org/10.3390/ijerph192013421	The FACHS Study
12	2022	Lei MK, Berg MT, Simons RL, Beach SRH.	Neighborhood structural disadvantage and biological aging in a sample of Black middle age and young adults. Soc Sci Med.	The FACHS Study
13	2022	Avila-Rieger, Justina, Indira C. Turney, Jet M.J. Vonk, Precious Esie, Dominika Seblova, Vanessa R. Weir, Daniel W. Belsky, Jennifer J. Manly	Socioeconomic Status, Biological Aging, and Memory in a Diverse National Sample of Older US Men and Women. Neurology 99 (19) e2114-e2124; DOI: 10.1212/WNL.0000000000201032.	Health and Retirement Study
14	2022	Graf Gloria H, Christopher L Crowe, Meeraj Kothari, Dayoon Kwon, Jennifer J Manly, Indira C Turney, Linda Valeri, Daniel W Belsky.	Testing Black-White Disparities in Biological Aging Among Older Adults in the United States: Analysis of DNA-Methylation and Blood-Chemistry Methods, American Journal of Epidemiology, Volume 191, Issue 4, April 2022, Pages 613–625, https://doi.org/10.1093/aje/kwab281	Health and Retirement Study
15	2022	Graf Gloria Huei-Jong, Yalu Zhang, Benjamin W Domingue, Kathleen Mullan Harris, Meeraj Kothari, Dayoon Kwon, Peter Muennig, Daniel W Belsky	Social mobility and biological aging among older adults in the United States, PNAS Nexus, Volume 1, Issue 2, pgac029, https://doi.org/10.1093/pnasnexus/pgac029.	Health and Retirement Study
16	2022	Kelly E. Rentscher, Eric T. Klopack, Eileen M. Crimmins, Teresa E. Seeman, Steve W. Cole, Judith E. Carroll	Lower Social Support is Associated with Accelerated Epigenetic Aging: Results from the Health and Retirement Study. medRxiv 2022.06.03.22275977; doi: https://doi.org/10.1101/2022.06.03.22275977.	Health and Retirement Study
17	2022	Schmitz, Lauren L. & Duque, Valentina	In-utero exposure to the Great Depression is reflected in late-life epigenetic aging signatures. PNAS, 119 (46) e2208530119. https://doi.org/10.1073/pnas.2208530119.	Health and Retirement Study
18	2022	Peterson, Mark D. Stacey Collins, Helen C.S. Meier, Alexander Brahmsteadt, Jessica D. Faul	Grip strength is inversely associated with DNA methylation age acceleration. J of Cachexia, sarcopenia, and muscle. https://doi.org/10.1002/jcsm.13110.	Health and Retirement Study
19	2022	Schmitz LL, Zhao W, Ratliff SM, Goodwin J, Miao J, Lu Q, Guo X, Taylor KD, Ding J, Liu Y, Levine M, Smith JA.	The Socioeconomic Gradient in Epigenetic Ageing Clocks: Evidence from the Multi-Ethnic Study of Atherosclerosis and the Health and Retirement Study. Epigenetics. 2022 Jun;17(6):589-611. doi: 10.1080/15592294.2021.1939479	MESA (Multi-ethnic Study of Atherosclerosis) and the Health and Retirement Study
20	2022	Reed RG, Carroll JE, Marsland AL, Manuck SB.	DNA methylation-based measures of biological aging and cognitive decline over 16-years: preliminary longitudinal findings in midlife. Aging; 14:9423-9444. https://doi.org/10.18632/aging.204376.	AHAB Study (Adult Health and Behavior Pittsburgh)
21	2022	McCrory C, Fiorito G, O'Halloran AM, Polidoro S, Vineis P, Kenny RA.	Early life adversity and age acceleration at mid-life and older ages indexed using the next-generation GrimAge and Pace of Aging epigenetic clocks. Psychoneuroendocrinology. Mar;137:105643. doi: 10.1016/j.psyneuen.2021.105643. .	TILDA (the Irish Longitudinal Study of Aging)
22	2022	Jesse R. Poganik, Bohan Zhang, Gurpreet S. Baht, Csaba Kerepesi, Sun Hee Yim, Ake T. Lu, Amin Haghani, Tong Gong, Anna M. Hedman, Ellika Andolf, Göran Pershagen, Catarina Almqvist, James P. White, Steve Horvath, Vadim N. Gladyshev.	Biological age is increased by stress, and restored upon recovery from stress, BioRxiv.	Three Clinical Datasets
23	2022	Michael Safaee, Varun Dwaraka, Justin K. Scheer, Marissa Fury, Tavis Mendez, Ryan Smith, Jue Lin, Dana Smith, Christopher P. Ames,	Cellular aging for risk stratification in adult deformity surgery: utilization of seven epigenetic clocks and two telomere length measurements in the analysis of comorbidity burden, frailty, disability and complications in adult deformity surgery, The Spine Journal, Volume 22, Issue 9, Supplement, 2022, Pages S13-S14, ISSN 1529-9430, https://doi.org/10.1016/j.spinee.2022.06.041.	Clinical sample.
24	2022	Sugden, K., A. Caspi, ML Elliott, KJ Bourassa, K Chamarti, DL Corcoran, AR Hariri, RM Houts, Meeraj Kothari, S Kritchevsky, GA Kuchel, J Mill. BS Williams, DW Belsky, TE Moffitt	Association of Pace of Aging measured by blood-based DNA methylation with age related cognitive decline and dementia. Neurology	ADNI Study (Alzheimers Disease Neuroimaging Initiative), Framingham Offspring Study
25	2022	Sugden, Karen, Terrie E. Moffitt, Thalida Em Arpawong, Daniel W. Belsky, David L. Corcoran, Eileen M. Crimmins, Eilis Hannon, Renate Houts, Jonathan S. Mill, Richie Poulton, Sandyha Ramrakha, Jasmin Wertz, Benjamin S. Williams, Avshalom Caspi	Cross-national and cross-generational evidence that educational attainment may slow the pace of aging. J of Gerontology	Health and Retirement Study, Generation Scotland, E-Risk Study, UK Understanding Society, Dunedin Study
26	2022	Belsky, DW, A Caspi, D Corcoran, K Sugden, R Poulton, L Arseneault, A Baccarelli, K Chamarti, X Goa, E Hannon,, HL Harrington, R Houts, M Kotharti, D Kwon, J Mill, J Schwartz, P Vokonas, C Wang, B Williams, TE Moffitt	DunedinPACE, A DNA methylation biomarker of the Pace of Aging, eLife.	Dunedin Study, Normative Aging Study, E-Risk Study, Framingham Heart Study, UK Understanding Society
27	2022	Ruiz, Begoña, Jonathan M. Broadbent, W. Murray Thomson, Sandhya Ramrakha, Terrie E. Moffitt, Avshalom Caspi, Richie Poulton.	Childhood caries is associated with poor health and a faster pace of ageing by midlife.	Dunedin Study
28	2022	Bourassa, K. J., Moffitt, T. E. Ambler, A., Hariri, A., Harrington, H. L., Houts, R. M., Ireland, D., Knodt, A., Poulton, R., Ramrakha, S., Caspi, A.	Accelerated aging in midlife is antedated by treatable adolescent health conditions. JAMA Pediatrics https://jamanetwork.com/journals/jamapediatrics/fullarticle/2789349	Dunedin Study
29	2022	Meier, Madeline H., Avshalom Caspi, Antony Ambler, Ahmad R. Hariri, HonaLee Harrington, Sean Hogan, Renate Houts, Annchen R. Knodt, Sandhya Ramrakha, Leah Richmond-Rakerd, Richie Poulton Terrie E. Moffitt	Long-term Cannabis Users’ Preparedness for Healthy Aging: A Population-Representative Longitudinal Study. Lancet Healthy Longevity	Dunedin Study
30	2022	Langevin, S., Caspi, A., Barnes, J.C, Brennan, G., Poulton, R., Purdy, S., Tanksley, P.T., Thorne, P., Wilson, G., & Moffitt, T.E.	Life-course persistent antisocial behavior and accelerated biological aging in a longitudinal birth cohort. International Journal of Environmental Research and Public Health	Dunedin Study
31	2022	Bourassa, K. J., Caspi, A., Hall, K. S., Harrington, H. L., Houts, R. M., Kimbrel, N. A., Poulton, R., Ramrakha, S., Taylor, G. A., & Moffitt, T. E.	Which measures of stress best predict accelerated biological aging? Comparing perceived stress, stressful life events, and posttraumatic stress disorder. Under review.	Dunedin Study
32	2021	Simons, R. L., Lei, M.-K., Klopach, E., Berg, M., Zhang, Y., & Beach, S. S. R.	(Re)Setting Epigenetic Clocks: An Important Avenue Whereby Social Conditions Become Biologically Embedded across the Life Course. Journal of Health and Social Behavior, 62(3), 436–453. https://doi.org/10.1177/00221465211009309.	The FACHS Study (Family and Community Health Study of African American Families)
33	2021	Kuo, P.-L., Moore, A. Z., Lin, F. R., & Ferrucci, L.	Epigenetic age acceleration and hearing: Observations from the Baltimore Longitudinal Study of Aging. Frontiers in Aging Neuroscience, 13, Article 790926. https://doi.org/10.3389/fnagi.2021.790926.	BLSA (Baltimore Longitudinal Study of Aging)
34	2021	Wertz, Jasmin, Avshalom Caspi, Antony Ambler, Jonathan Broadbent, Robert J. Hancox, HonaLee Harrington, Renate M. Houts, Joan H. Leung, Richie Poulton, Suzanne C. Purdy, Sandhya Ramrakha, Line Jee Hartmann Rasmussen, Leah S. Richmond-Rakerd, Peter R. Thorne, Graham A. Wilson, Terrie E. Moffitt	History of psychiatric illness as a risk factor for accelerated aging: Evidence from a population-representative longitudinal cohort study. JAMA-Psychiatry	Dunedin Study
35	2021	Elliott, Max, Avshalom Caspi, RM Houts, A Ambler, JM Broadbent, RJ Hancox, HL Harrinton, S Hogan, R Keenan, A Knodt, JH Leung, TR Melzer, SC Purdy, S Ramrakha, LS Richmond-Rakerd, A Righarts, K Sugden, WM Thomson, PR thorne, BS Williams, G Wilson, AR Hariri, R Poulton, TE Moffitt .	Disparities in the pace of biological aging among midlife adults of the same chronological age: Implications for future frailty risk and policy. Nature Aging https://rdcu.be/cgNdq	Dunedin Study
36	2021	Richmond-Rakerd, Leah S., Avshalom Caspi, Antony Ambler Tracy d’Arbeloff, Marieke de Bruine, Maxwell Elliott, HonaLee Harrington, Sean Hogan, Renate M. Houts, David Ireland, Ross Keenan, Annchen R. Knodt, Tracy R. Melzer, Sena Park, Richie Poulton, Sandhya Ramrakha, Line Jee Hartmann Rasmussen, Elizabeth Sack, Adam T. Schmidt, Maria L. Sison, Jasmin Wertz, Ahmad R. Hariri, & Terrie E. Moffitt	Childhood self-control forecasts the pace of midlife aging and preparedness for old age. PNAS https://www.pnas.org/content/118/3/e2010211118	Dunedin Study
37	2020	Belsky, DW, A Caspi, L Arseneault, Baccarelli, A., D Corcoran, Gao, X, Hannon, HL Harrington, L J Rassmussen, R Houts, K Huffman, WE Kraus, Kwon, D, J Mill, C Pieper, J Prinz, R Poulton, Schwartz, J, K Sugden, Vokonas, P, B Williams, TE Moffitt	Quantification of the pace of biological aging in humans through a blood test: The DunedinPoAm DNA methylation algorithm, eLife https://elifesciences.org/articles/54870	Dunedin Study, Normative Aging Study, E-Risk Study, UK Understanding Society
38	2020	Bourassa, K. J., Caspi, A., Harrington, H. L., Houts, R. M., Poulton, R., Ramrakha, S., & Moffitt, T. E. .	Intimate partner violence and lower relationship quality are associated with faster biological aging. Psychology and Aging	Dunedin Study
39	2020	Rasmussen, LJ, A Caspi, A Ambler, A Danese, M Elliott, J Eugen-olsen, A Hariri, HL Harrington, R Houts, R Poulton, S Ramrakha, K Sugden, B Williams, TE Moffitt.	Association between elevated suPAR, a new biomarker of chronic inflammation, and accelerated aging. Journal of Gerontology, Medical Sciences	Dunedin Study
40	2019	Elliott, Maxwell L. Daniel W. Belsky, Annchen R. Knodt, David Ireland, Tracy R. Melzer, Richie Poulton, Sandhya Ramrakha, Avshalom Caspi, Terrie E. Moffitt, Ahmad R. Hariri	Brain-age in midlife is associated with accelerated biological aging and cognitive decline in a longitudinal birth-cohort. Molecular Psychiatry	Dunedin Study
41	2017	Belsky DW, Caspi A, Cohen HJ, Kraus WE, Ramrakha S, Poulton R, Moffitt TE.	Impact of Early Personal History Characteristics on the Pace of Aging: Implications for Clinical Trials of Therapies to Slow Aging and Extend Healthspan. Aging Cell.	Dunedin Study
42	2017	Belsky DW, Moffitt TE, Cohen AA, Corcoran DL, Levine ME, Prinz J, Schaefer J, Sugden K, Williams B, Poulton R, Caspi A.	Eleven telomere, epigenetic clock, and biomarker-composite quantifications of biological aging: Do they measure the same thing? American J of Epidemiology. doi: http://dx.doi.org/10.1101/071373	Dunedin Study
43	2015	Belsky DW, Caspi A, Houts R, Cohen HJ, Corcoran D, Danese A, Harrington HL, Israel S, Levine ME, Schaefer J, Sugden K, Williams B, Yashin A, Poulton R, Moffitt TE.	Quantification of biological aging in young adults. Proceedings of the National Academy of Sciences of the United States of America. 77, 601-617.	Dunedin Study
44		Simons, R., Ong, M., Lei, M., Klopack, E., Berg, M., Zhang, Y., Philibert, R., & Beach, S.	Unstable Childhood, Adult Adversity, and Smoking Accelerate Biological Aging Among Middle-Age African Americans: Similar Findings for GrimAge and PoAm. J of Aging and Health 089826432110436. 10.1177/08982643211043668.	The FACHS Study